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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Z-DNA binding protein 1

Dai, ZBP1
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] (from NCBI)
Top mentioned proteins: CAN, Actin, HAD, ACID, beta-actin
Papers using Dai antibodies
Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate
Chen Xiaoyuan et al., In Theranostics, 2008
... DaiHPreparation of carbon nanotube bioconjugates for biomedical applications ...
ZBP1 regulates mRNA stability during cellular stress
Hüttelmaier Stefan et al., In The Journal of Cell Biology, 2004
... Full-length chicken ZBP1 or ZBP1 deletion fragments were generated by PCR, verified by sequencing, and inserted in pEGFP (CLONTECH Laboratories, Inc.) or mRFP ...
Papers on Dai
Radiocesium accumulation properties of Chengiopanax sciadophylloides.
Takenaka et al., Nagoya, Japan. In J Environ Radioact, Jan 2016
Through the assessments of radioactive contamination after the Fukushima Dai-ichi Nuclear Power Plant (F1NPP) accident, it has been reported that some sprouts of Chengiopanax sciadophylloides (Franch.
Activation of TLR3/interferon signaling pathway by bluetongue virus results in HIV inhibition in macrophages.
Ho et al., Philadelphia, United States. In Faseb J, Dec 2015
These findings demonstrate the potential of BTV-mediated TLR3 activation in macrophage innate immunity against HIV.-Dai, M., Wang, X., Li, J.-L., Zhou, Y., Sang, M., Liu, J.-B., Wu, J.-G., Ho, W.-Z. Activation of TLR3/interferon signaling pathway by bluetongue virus results in HIV inhibition in macrophages.
How do reducing equivalents increase insulin secretion?
Attie, In J Clin Invest, Nov 2015
In this issue, Ferdaoussi, Dai, and colleagues reveal that insulin secretion is amplified by cytosolic isocitrate dehydrogenase-dependent transfer of reducing equivalents, which generates NADPH and reduced glutathione, which in turn activates sentrin/SUMO-specific protease-1 (SENP1).
Prevalence of hemoglobin E in Yunnan Province of Southwest China.
Zhu et al., In Hematology, Sep 2015
Dai (16.0%), and Lisu (13.6%).
Quantifying Protein-mRNA Interactions in Single Live Cells.
Singer et al., United States. In Cell, Aug 2015
We applied this to quantify the known binding of zipcode binding protein 1 (ZBP1) and ribosomes to β-actin mRNA within subcellular compartments of primary fibroblasts and neurons.
Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China.
Huang et al., Kunming, China. In Genet Mol Res, 2014
The correlation analysis between NPR3 and hypertension was replicated in 450 Chinese Dai (235 patients vs 215 controls) and 484 Chinese Mongolian (211 patients vs 273 controls) individuals.
A Novel Role for VICKZ Proteins in Maintaining Epithelial Integrity during Embryogenesis.
Yisraeli et al., Jerusalem, Israel. In Plos One, 2014
BACKGROUND: VICKZ (IGF2BP1,2,3/ZBP1/Vg1RBP/IMP1,2,3) proteins bind RNA and help regulate many RNA-mediated processes.
Endothelin-1 and its role in the pathogenesis of infectious diseases.
Desruisseaux et al., United States. In Life Sci, 2014
Clinical and experimental data indicate that ET-1 is involved in the pathogenesis of sepsis (Tschaikowsky et al., 2000; Goto et al., 2012), viral and bacterial pneumonia (Schuetz et al., 2008; Samransamruajkit et al., 2002), Rickettsia conorii infections (Davi et al., 1995), Chagas disease (Petkova et al., 2000, 2001), and severe malaria (Dai et al., 2012; Machado et al., 2006; Wenisch et al., 1996a; Dietmann et al., 2008).
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.
Mocarski et al., Atlanta, United States. In Cell Host Microbe, 2012
DAI interacts with RIP3 to mediate virus-induced necrosis analogous to the RIP1-RIP3 complex controlling death receptor-induced necroptosis.
Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning.
Czaplinski et al., New York City, United States. In Learn Mem, 2012
The data of this study suggest that RNA-binding proteins can be used as a tool to identify the post-transcriptional regulation of gene expression in the establishment and function of neural circuits involved in addiction behaviors.
The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA.
Wolin et al., New Haven, United States. In Rna, 2012
these data indicate that ZBP1 may function as an adapter to export the Ro/Y3 RNA complex from nuclei.
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity.
Twiss et al., Newark, United States. In Embo J, 2011
data support a direct role for ZBP1 in transport and translation of mRNA cargos in axonal regeneration in vitro and in vivo
Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs.
Jeon et al., Suwŏn, South Korea. In Proc Natl Acad Sci U S A, 2011
Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs.
Nucleic acid sensing receptors in systemic lupus erythematosus: development of novel DNA- and/or RNA-like analogues for treating lupus.
Lenert, Iowa City, United States. In Clin Exp Immunol, 2010
Thus, endosomal Toll-like receptors (TLR) mediate responses to double-stranded RNA (TLR-3), single-stranded RNA (TLR-7/8) or unmethylated bacterial cytosine (phosphodiester) guanine (CpG)-DNA (TLR-9), while DNA-dependent activator of IRFs/Z-DNA binding protein 1 (DAI/ZBP1), haematopoietic IFN-inducible nuclear protein-200 (p202), absent in melanoma 2 (AIM2), RNA polymerase III, retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) mediate responses to cytosolic dsDNA or dsRNA, respectively.
The innate immune response to DNA.
Muruve et al., Calgary, Canada. In Semin Immunol, 2009
Recently, novel cytosolic DNA sensors have been uncovered that include ZBP1 or DNA-dependent activator of interferon-regulatory factors (DAI) and a DNA sensing inflammasome consisting of the HIN200 protein, absent in melanoma 2 (AIM2).
Regulation of the cytosolic DNA-sensing system in innate immunity: a current view.
Taniguchi et al., Tokyo, Japan. In Curr Opin Immunol, 2009
In particular, DAI (DLM-1/ZBP1), Trex1, and other regulators of the cytosolic DNA-sensing system have recently been identified and characterized.
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines.
Akira et al., Japan. In Nature, 2008
Plasmid-DNA-activated, TBK1-dependent signalling and the resultant type-I interferon receptor-mediated signalling was required for induction of antigen-specific B and T cells, which occurred even in the absence of innate immune signalling through a well known CpG DNA sensor-Toll-like receptor 9 (TLR9) or Z-DNA binding protein 1 (ZBP1, also known as DAI, which was recently reported as a potential B-form DNA sensor).
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
Taniguchi et al., Tokyo, Japan. In Nature, 2007
observations underscore an integral role of DAI (DLM-1/ZBP1) in the DNA-mediated activation of innate immune responses
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.
Singer et al., New York City, United States. In Nature, 2005
This localization requires the oncofetal protein ZBP1 (Zipcode binding protein 1), which binds to a conserved 54-nucleotide element in the 3'-untranslated region of the beta-actin mRNA known as the 'zipcode'.
TRPV1 Receptors and Signal Transduction
Simon et al., Boca Raton, United States. In Unknown Journal, 0001
Similar to many other channels, TRPV1 contains multiple phosphorylation sites in its amino acid sequence for protein kinase C (PKC) (Bhave et al., 2003; Dai et al., 2004; Premkumar et al., 2004), protein kinase A (PKA) (Bhave et al., 2002; De Petrocellis et al., 2001; Rathee et al., 2002) and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII).
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