Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome.
Chongqing, China. In Cell Mol Neurobiol, Sep 2015
Specifically, three key aspects were examined: (a) whether the expression of Daam2, disheveled-associated activator of morphogenesis, a key Wnt signaling downstream effector, and PIP5K is changed in the demyelinating conditions and under different stages of progress of clinical recovery of patients with Guillain-Barre syndrome; (b) whether critical protein interactions of Daam2 with disheveled and Arf6 are changed; and (c) whether expression of c-Jun/Krox, a key negative regulator of remyelination, is changed.
Atmin mediates kidney morphogenesis by modulating Wnt signaling.
London, United Kingdom. In Hum Mol Genet, 2014
Instead, Gpg6 homozygous kidneys exhibited altered cytoskeletal organization and modulation of Wnt signaling pathway molecules, including β-catenin and non-canonical Wnt/planar cell polarity (PCP) pathway factors, such as Daam2 and Vangl2.
Your gut is right to turn left.
Seattle, United States. In Dev Cell, 2013
(2013) identify the formin Daam2, an effector of Wnt signaling, as a key cellular target of Pitx2 required for morphogenetic events during asymmetric gut formation.
Genetic variants contribute to gene expression variability in humans.
College Station, United States. In Genetics, 2013
Using a data set of gene expression in lymphoblastoid cell lines (LCLs) derived from 210 HapMap individuals, we identify cis-acting evQTL involving 218 distinct genes, among which 8 genes, ADCY1, CTNNA2, DAAM2, FERMT2, IL6, PLOD2, SNX7, and TNFRSF11B, are cross-validated using an extra expression data set of the same LCLs.
Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis.
Tokyo, Japan. In Stem Cell Rev, 2007
In 2003, we identified and characterized PRICKLE1, PRICKLE2, DACT1/DAPPER1, DACT2/DAPPER2, DAAM2, and BCL9L.
WNT/PCP signaling pathway and human cancer (review).
Tokyo, Japan. In Oncol Rep, 2005
Dishevelled-dependent WNT/PCP signals are transduced to the RHOA signaling cascade through Formin homology proteins DAAM1 and DAAM2, and to the JNK signaling cascade through MAPKKKs and MAPKK4/7.