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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Cancer susceptibility candidate 5

D40, Spc105, AF15q14, KNL-1
Top mentioned proteins: CAN, HEC, HAD, ACID, Mis12
Papers on D40
Monitoring of embryonic and fetal losses in different breeds of goats using real-time B-mode ultrasonography.
New
Watanabe et al., Al Jīzah, Egypt. In Theriogenology, Feb 2016
Goats (n = 151) of different breeds (70 Zaraiebi, 42 Damascus, and 39 Cross goats [Baladi × Damascus]) were evaluated by ultrasonography to monitor EFL during different stages of gestation (D20-23, D26-29, D33-36, D40-45, and D47-54 after breeding).
ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.
New
Wang et al., Shanghai, China. In Oncotarget, Jan 2016
Using protein affinity purification methods, we searched for functional partners of ASPP1/2, and found that ASPP1/2 were associated with a subset of kinetochore proteins (Hec1, KNL-1, and CENP-F).
Transient reduction in venous susceptibility during posterior reversible encephalopathy syndrome.
New
Bertrand et al., Brest, France. In J Neurol Sci, Dec 2015
The progressive normalization of venous signal on D10 and D40 imaging paralleled the progressive decrease of hyperperfusion on CBF images.
Clinical efficacy and cardiorespiratory effects of intramuscular administration of alfaxalone alone or in combination with dexmedetomidine in cats.
New
Laredo et al., Merelbeke, Belgium. In Vet Anaesth Analg, Nov 2015
METHODS: Cats were assigned randomly to each of three treatments: A5 (alfaxalone 5 mg kg(-1) ), D20 A5 (dexmedetomidine 20 μg kg(-1) and alfaxalone 5 mg kg(-1) ) and D40 A5 (dexmedetomidine 40 μg kg(-1) and alfaxalone 5 mg kg(-1) ).
Metrics and statistics of frequency of occurrence of metamerism in consumer cameras for natural scenes.
New
Wenhe et al., In J Opt Soc Am A Opt Image Sci Vis, Aug 2015
This paper presents metrics and statistics of frequency of occurrence of metamerism in three consumer cameras, viz., Canon 1D Mark III, Nikon D40, and Sony α7, using spectral and RGB images of natural scenes.
The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signalling.
New
Impact
Joglekar et al., Ann Arbor, United States. In Nat Cell Biol, Jul 2015
Here we show that, in budding yeast, end-on microtubule attachment to the kinetochore physically separates the Mps1 kinase, which probably binds to the calponin homology domain of Ndc80, from the kinetochore substrate of Mps1, Spc105 (KNL1 orthologue).
Kinetochore components are required for central spindle assembly.
New
Impact
Dumont et al., Paris, France. In Nat Cell Biol, May 2015
Specifically, central spindle microtubule assembly is dependent on kinetochore recruitment of the scaffold protein KNL-1, as well as downstream partners BUB-1, HCP-1/2(CENP-F) and CLS-2(CLASP); and is negatively regulated by kinetochore-associated protein phosphatase 1 activity.
Targeted Knockdown of the Kinetochore Protein D40/Knl-1 Inhibits Human Cancer in a p53 Status-Independent Manner.
Takimoto et al., Sapporo, Japan. In Sci Rep, 2014
The D40 gene encodes a kinetochore protein that plays an essential role in kinetochore formation during mitosis.
An Investigation on Formaldehyde Emission Characteristics of Wood Building Materials in Chinese Standard Tests: Product Emission Levels, Measurement Uncertainties, and Data Correlations between Various Tests.
Zhang et al., Beijing, China. In Plos One, 2014
The PFE of fiberboards, particleboards, blockboards, floorings, and parquets manufactured in Beijing region were characterized by the perforator extraction method (PE), 9-11 L and 40 L desiccator methods (D9, D40), and environmental chamber method (EC) of the Chinese national standard GB 18580; based on statistics of PFE data, measurement uncertainties in CST were evaluated by the Monte Carlo method; moreover, PFE data correlations between tests were established.
Organochlorine pesticides (OCPs) in wetland soils under different land uses along a 100-year chronosequence of reclamation in a Chinese estuary.
Zhang et al., Beijing, China. In Sci Rep, 2014
Both D30 and D20 soils contained the highest ∑OCP levels, followed by D40 and D100 soils; lower ∑OCP levels occurred in D10 soils.
Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.
Review
Wynne et al., New York City, United States. In Chromosoma, 2013
Spindle assembly checkpoint (SAC) signaling, which is activated by unattached kinetochores and inhibits the metaphase-to-anaphase transition, depends on kinetochore recruitment of the kinase Bub1 through Mps1-mediated phosphorylation of the kinetochore protein KNL1 (also known as Blinkin in mammals, Spc105 in budding yeast, and Spc7 in fission yeast).
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore.
Impact
GeneRIF
De Wulf et al., Milano, Italy. In Nat Cell Biol, 2012
Cnn1 regulates KMN (KNL1, MIS12 and NDC80 activity in a spatiotemporal manner by inhibiting the interaction between its complexes
Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site.
GeneRIF
Blundell et al., Cambridge, United Kingdom. In Structure, 2011
we identify the Blinkin motif critical for interaction with BUBR1, define the stoichiometry and affinity of the interaction, and present a 2.2 Angstrom resolution crystal structure of the complex
Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1.
GeneRIF
Yanagida et al., Kyoto, Japan. In Mol Cell Biol, 2011
h-KNL1 functions to connect Bub1 and BubR1 with the hMis12, Ndc80, and Zwint-1 complexes.
Testis cancer gene D40 expression and its relationship with clinicopathological features in infertile men.
GeneRIF
Tsukamoto et al., Sapporo, Japan. In Int J Urol, 2011
Expression levels of D40 mRNA and proteins decrease according to the degree of spermatogenesis impairment in male infertile patients.
A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis.
Impact
Desai et al., San Diego, United States. In Nat Cell Biol, 2010
Here, we show in Caenorhabditis elegans oocytes that the kinetochore protein, KNL-1, directs assembly of meiotic kinetochores that orient chromosomes.
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase.
GeneRIF
Lampson et al., Philadelphia, United States. In J Cell Biol, 2010
phosphorylation of KNL1 by Aurora B disrupts the KNL1-PP1 interaction
Mechanisms of force generation by end-on kinetochore-microtubule attachments.
Review
Salmon et al., Chapel Hill, United States. In Curr Opin Cell Biol, 2010
In recent years, the KMN network of proteins (Ndc80 complex, Mis12 complex, and KNL-1 complex) has emerged as a highly conserved core microtubule-binding complex at the kinetochore.
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore.
Impact
Desai et al., Los Angeles, United States. In Cell, 2007
Here, we examined the conserved KNL-1/Mis12 complex/Ndc80 complex (KMN) network, which is essential for kinetochore-microtubule interactions in vivo.
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