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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ElaC homolog 1

D29, tRNA 3' processing endoribonuclease, ELAC1, tRNase Zs
Top mentioned proteins: HAD, CAN, Rab3D, Hoxa5, ACID
Papers on D29
Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats.
New
Boyce et al., Thousand Oaks, United States. In Bone, Jan 2016
Bone formation rate (BFR/bone surface [BS]) and total OB number increased through d29, then progressively declined, coincident with a decrease in total osteoprogenitor (OP) numbers from d29 through d183.
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.
New
Harbo et al., Leuven, Belgium. In Brain, Mar 2015
Furthermore, we identify a novel association signal of rs9807334, near the ELAC1/SMAD4 genes, for oligoclonal band status (P = 8.45 × 10(-7)).
Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.
Försti et al., Heidelberg, Germany. In Cancer Causes Control, 2014
METHODS: After excluding the well-established CRC genes APC, KRAS, TP53, and ABCA1, we analyzed 35 potentially functional single-nucleotide polymorphisms (SNPs) in 10 CAN genes (OBSCN, MLL3, PKHD1, SYNE1, ERCC6, FBXW7, EPHB6/TRPV6, ELAC1/SMAD4, EPHA3, and ADAMTSL3) using KBiosciences Competitive Allele-Specific PCR™ genotyping assays.
Analysis of bevacizumab-based preoperative radiochemotherapy in patients with locally advanced rectal cancer on surgery-associated spectrum of complications.
Zühlke et al., Kiel, Germany. In Ann Surg Oncol, 2014
Gy fractions), simultaneous bevacizumab 5 mg/kg (d1, d15, d29), and capecitabine 825 mg/m(2) twice daily (d1-14, d22-35), oxaliplatin 50 mg/m(2) (d1, d8, d22, d29).
Optimal time to use low molecular weight heparin on prethrombotic state of rat chronic obstructive pulmonary disease model.
Tong et al., Qingdao, China. In Chin Med J (engl), 2013
METHODS: Forty Wistar rats were randomly divided into 4 groups: normal control, raised for 55 days without any treatment; COPD control without LMWH, cigarette inhalation plus intratracheal instillation of lipopolysaccharide and hypodermic injection of normal saline once a day for 10 days; COPD control given LMWH 150 U/kg subcutaneous injection, once a day for 10 days starting day 15 (LMWH-d15); COPD control given LMWH 150 U/kg subcutaneous injection, once a day for 10 days starting day 29 (LMWH-d29).
Evidence of airborne excretion of Pneumocystis carinii during infection in immunocompetent rats. Lung involvement and antibody response.
Derouin et al., Paris, France. In Plos One, 2012
P. carinii DNA was detected in lungs until d29 in two separate experiments and thereafter remained undetectable.
Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer.
Dunst et al., In Radiat Oncol, 2012
Patients received conventionally fractionated radiotherapy (50.4 Gy in 1.8 Gy fractions) and simultaneous chemotherapy with capecitabine 825 mg/m2 bid (d1-14, d22-35) and oxaliplatin 50 mg/m2 (d1, d8, d22, d29).
[A multi-centered randomized controlled study of neo-adjuvant chemoradiotherapy followed by surgery versus surgery alone for locally advanced squamous cell carcinoma of esophagus: an interim analysis].
LI et al., Guangzhou, China. In Zhonghua Yi Xue Za Zhi, 2012
Vinorelbine at 25 mg/m(2) per day was administered as a bolus infusion at d1, d8, d22 and d29.
Identification and sequence analysis of metazoan tRNA 3'-end processing enzymes tRNase Zs.
Huang et al., Nanjing, China. In Plos One, 2011
tRNase Z is the endonuclease responsible for removing the 3'-trailer sequences from precursor tRNAs, a prerequisite for the addition of the CCA sequence.
Triple induction chemotherapy and chemoradiotherapy for locally advanced esophageal cancer. A phase II study.
Ofner et al., Innsbruck, Austria. In Anticancer Res, 2011
BACKGROUND: This phase II trial assessed the feasibility and safety of induction chemotherapy with cisplatin (25 mg/m(2) d1-5, d29-34)/docetaxel (75 mg/m(2) d1, d29)/5-fluorouracil (5-FU, 750 mg/m(2) d1-5, d 29-34) followed by external beam radiotherapy concurrent with docetaxel (15 mg/m(2) d1,8,15,22) and 5-FU (300 mg/m(2) continuous infusion on the days of radiotherapy).
RNAi knockdown of dRNaseZ, the Drosophila homolog of ELAC2, impairs growth of mitotic and endoreplicating tissues.
Dubrovsky et al., United States. In Insect Biochem Mol Biol, 2011
The Drosophila RNase Z(L) (dRNaseZ) gene encodes a member of the ELAC1/ELAC2 protein family with homologs in every living organism.
High white blood cell count at diagnosis of childhood acute lymphoblastic leukaemia: biological background and prognostic impact. Results from the NOPHO ALL-92 and ALL-2000 studies.
Nordic Society of Paediatric Haematology and Oncology (NOPHO) et al., Vilnius, Lithuania. In Eur J Haematol, 2011
WBC was not associated with risk of event for BCP or T-ALL for patients with minimal residual disease at the end of induction (MRD(d29) ) <10(-3).
A survey of green plant tRNA 3'-end processing enzyme tRNase Zs, homologs of the candidate prostate cancer susceptibility protein ELAC2.
Huang et al., Nanjing, China. In Bmc Evol Biol, 2010
tRNase Z exists in the short (tRNase ZS) and long (tRNase ZL) forms.
Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation.
Rossmanith, Vienna, Austria. In Plos One, 2010
Human cells contain a long form (RNase Z(L)) encoded by ELAC2, and a short form (RNase Z(S); ELAC1).
Identification and analysis of candidate fungal tRNA 3'-end processing endonucleases tRNase Zs, homologs of the putative prostate cancer susceptibility protein ELAC2.
Huang et al., Nanjing, China. In Bmc Evol Biol, 2009
BACKGROUND: tRNase Z is the endonuclease that is responsible for the 3'-end processing of tRNA precursors, a process essential for tRNA 3'-CCA addition and subsequent tRNA aminoacylation.
Regulation of the human tRNase ZS gene expression.
GeneRIF
Nashimoto et al., Niigata, Japan. In Febs Lett, 2008
Human tRNase ZS gene expression appears to be post-transcriptionally regulated.
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