Global profiling of the signaling network of papillary thyroid carcinoma.
New York City, United States. In Life Sci, Feb 2016
KEY FINDINGS: 11 were differentially expressed between tumors and surrounding tissues, 8 of which were up-regulated (cytokeratin 18, Stat 1, HMG-1, p-p70 S6 kinase, Raf-B, glutamine synthetase, p-PKC δ, and HDAC1), while 3 of which were down-regulated (cytokeratin 5, BECN1, and p-ERK).
A liver-on-a-chip platform with bioprinted hepatic spheroids.
Boston, United States. In Biofabrication, Dec 2015
The engineered hepatic construct remained functional during the 30 days culture period as assessed by monitoring the secretion rates of albumin, alpha-1 antitrypsin, transferrin, and ceruloplasmin, as well as immunostaining for the hepatocyte markers, cytokeratin 18, MRP2 bile canalicular protein and tight junction protein ZO-1.
Drug-induced liver injury: the dawn of biomarkers?
Zürich, Switzerland. In F1000prime Rep, 2014
Proposed DILI indicators that are under investigation include microRNAs, cytokeratin-18 (CK18), high mobility group box protein 1 (HMGB-1), and several other biomarkers.