Light- and pH-activated intracellular drug release from polymeric mesoporous silica nanoparticles.
Winnipeg, Canada. In Colloids Surf B Biointerfaces, Nov 2015
Multimodal nonlinear optical imaging microscopy (NLOM) was employed to acquire in vitro coherent anti-Stokes Raman (CARS) and two-photon excited fluorescence (TPEF) images of live MCF-7 cells and showed that the nanoparticles can be taken up by breast tumor cell MCF-7 with high efficiency, indicating its great potential for anti-cancer drug delivery system.
Immunoproteomic profiling of Rickettsia parkeri and Rickettsia amblyommii.
Baton Rouge, United States. In Ticks Tick Borne Dis, Sep 2015
Serum specimens from patients with R. parkeri rickettsiosis reacted specifically with cysteinyl-tRNA synthetase, DNA-directed RNA polymerase subunit alpha, putative sigma (54) modulation protein, chaperonin GroEL, and elongation factor Tu of R. parkeri which have been reported as virulence factors in other bacterial species.
Seatbelts in CAR therapy: How Safe Are CARS?
Birmingham, United States. In Pharmaceuticals (basel), 2014
T-cells genetically redirected with a chimeric antigen receptor (CAR) to recognize tumor antigens and kill tumor cells have been infused in several phase 1 clinical trials with success.
The immune response to surgery and infection.
Warsaw, Poland. In Cent Eur J Immunol, 2013
Extensive surgery in cancer patients is associated with simultaneous activation of pro- and anti-inflammatory processes defined as SIRS (systemic inflammatory immune response) and CARS (compensatory anti-inflammatory immune response).