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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cystatin C

cystatin C
Top mentioned proteins: AGE, HAD, EGFR, Serum albumin, CAN
Papers using cystatin C antibodies
Surface Cathepsin B Protects Cytotoxic Lymphocytes from Self-destruction after Degranulation
Henkart Pierre A. et al., In The Journal of Experimental Medicine, 1998
... Human cystatin C was purchased from Research Diagnostics.
European standardized method for the determination of delta-aminolevulinic acid dehydratase activity in blood.
Luque Raul M., In PLoS ONE, 1973
... 11489364 216, Roche, Germany) or serum cystatin C concentration (Mouse Cystatin C ELISA, BioVendor GmbH) ...
Papers on cystatin C
Plasma endostatin may improve acute kidney injury risk prediction in critically ill patients.
Larsson et al., Sweden. In Ann Intensive Care, 31 Dec 2016
The aim of this study was to compare the AKI predictive value of plasma endostatin with two previously suggested biomarkers of AKI, cystatin C and neutrophil gelatinase-associated lipocalin (NGAL).
Reduced kidney function is a risk factor for atrial fibrillation.
Kurl et al., Kuopio, Finland. In Nephrology (carlton), Feb 2016
Cystatin C- and creatinine- based estimation of glomerular filtration rate (eGFRcys and eGRFcreat , respectively) and urinary albumin/creatinine ratio (ACR) were assessed to investigate their relationship with the risk of atrial fibrillation.
Can admission serum cystatin C level be an early marker subclinical acute kidney injury in critical care patients?
Gürsel et al., Ankara, Turkey. In Scand J Clin Lab Invest, Feb 2016
In this study we aimed to determine whether admission serum cystatin C (sCys-C) and other clinical parameters can identify subclinical AKI in medical intensive care unit (ICU) patients with normal creatinine-based eGFR at admission.
Assessment of glomerular filtration rate in the neonate: is creatinine the best tool?
Alvarez-Elías et al., London, Canada. In Curr Opin Pediatr, Feb 2016
This review summarizes current knowledge on the prenatal and postnatal handling of creatinine as well as that of other, more novel biomarkers of GFR, such as cystatin C (CysC) and β-trace protein (BTP).
Circulating Alpha-Tocopherol and Insulin Sensitivity Among Older Men With Chronic Kidney Disease.
Carrero et al., Stockholm, Sweden. In J Ren Nutr, Feb 2016
SETTING: A total of 273 nondiabetic men aged 70 to 71 years with CKD defined as either cystatin C estimated glomerular filtration rate < 60 mL/minute/1.73
Blood, urine and faecal metabolite profiles in the study of adult renal disease.
Menni et al., London, United Kingdom. In Arch Biochem Biophys, Feb 2016
Chronic kidney disease (CKD) is a major public health burden and to date traditional biomarkers of renal function (such as serum creatinine and cystatin C) are unable to identify at-risk individuals before the disease process is well under way.
A systematic review of biomarkers in the diagnosis of infective endocarditis.
Honoré et al., Århus, Denmark. In Int J Cardiol, Feb 2016
Based on current research, N-terminal-pro-B-type natriuretic peptide (NT-proBNP) alone or in combination with Cystatin C (Cys C), lipopolysaccharide-binding protein (LBP), troponins, aquaporin-9 (AQP9), S100 calcium binding protein A11 (S100A11), E-selectin (CD62E) and VCAM-1 (CD54) and interleukin-6 (IL-6) are potential biomarkers for future studies.
The correct renal function evaluation in patients with thyroid dysfunction.
Fuiano et al., Catanzaro, Italy. In J Endocrinol Invest, Nov 2015
Current data, in fact, demonstrate that either subclinical or overt thyroid disease is associated with significant changes in creatinine, estimated glomerular filtration rate, measured glomerular filtration rate and Cystatin C. Herein, we systematically reviewed several relevant studies aiming at the identification of the most sensitive and specific parameter for the correct renal function evaluation in patients with thyroid dysfunction, that are usually treated as outpatients.
Glomerular filtration rate and albuminuria for detection and staging of acute and chronic kidney disease in adults: a systematic review.
Inker et al., Boston, United States. In Jama, Mar 2015
If confirmation of GFR is required because of conditions that affect serum creatinine independent of GFR (eg, extremes of muscle mass or diet), or interference with the assay, cystatin C should be measured and estimated GFR should be calculated and reported using cystatin C (eGFRcys) and serum creatinine (eGFRcr-cys) or GFR should be measured directly using a clearance procedure.
Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial.
Cripe et al., Columbus, United States. In Lancet Neurol, Feb 2015
Safety was established through serial serum potassium levels and measurement of cystatin C, a non-creatinine measure of kidney function.
[Clinical Importance of GFR-Estimating Equations (eGFRcreat and eGFRcys)].
Horio, In Rinsho Byori, Feb 2015
The recent Japanese CKD guide and KDIGO guidelines for CKD management recommended the use of the estimated GFR based on serum creatinine (eGFRcreat) or serum cystatin C (eGFRcys).
The Importance of Accurately Assessing Renal Function in the Neonate and Infant.
Awuku et al., London, Canada. In Adv Clin Chem, 2014
Novel approaches for assessing neonatal renal function include cystatin C and beta-trace protein.
Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.
NHLBI Heart Failure Clinical Research Network et al., Montréal, Canada. In Jama, 2014
MAIN OUTCOMES AND MEASURES: Coprimary end points included 72-hour cumulative urine volume (decongestion end point) and the change in serum cystatin C from enrollment to 72 hours (renal function end point).
Cystatin C versus creatinine in determining risk based on kidney function.
CKD Prognosis Consortium et al., San Francisco, United States. In N Engl J Med, 2013
BACKGROUND: Adding the measurement of cystatin C to that of serum creatinine to determine the estimated glomerular filtration rate (eGFR) improves accuracy, but the effect on detection, staging, and risk classification of chronic kidney disease across diverse populations has not been determined.
Estimating glomerular filtration rate from serum creatinine and cystatin C.
CKD-EPI Investigators et al., Boston, United States. In N Engl J Med, 2012
Cystatin C is an alternative filtration marker for estimating GFR.
IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.
Villadangos et al., Australia. In J Immunol, 2011
Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.
Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development.
Holmdahl et al., Stockholm, Sweden. In Arthritis Res Ther, 2010
The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system
Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy.
Levy et al., United States. In Am J Pathol, 2010
Data show that cystatin C effectively rescues cystatin B loss-of-function mutation, facilitating the reversal of pathophysiological changes and suggesting a novel therapeutic intervention for patients with neurodegenerative disorders.
Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation.
Chen et al., Tucson, United States. In Cardiovasc Res, 2010
Oxidants induce elevated cystatin C production from cardiac myocytes. Cystatin C plays a role in cardiac extracellular matrix remodelling.
Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice.
Shi et al., Boston, United States. In Plos One, 2009
Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.
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