Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster.
In PLoS ONE, 2005
... weight fibroblast growth factor (lo-FGF Santa Cruz Biotechnology), HO-1 (Stressgen, Ann Arbor, MI, USA), cytochrome-c, HDAC5 (Cell Signaling, Danvers, MA, USA), HDAC1 ...
Biophysical regulation of epigenetic state and cell reprogramming.
San Francisco, United States. In Nat Mater, 31 Dec 2013
Specifically, decreased histone deacetylase activity and upregulation of the expression of WD repeat domain 5 (WDR5)-a subunit of H3 methyltranferase-by microgrooved surfaces lead to increased histone H3 acetylation and methylation.
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
Philadelphia, United States. In Nature, 03 Dec 2013
Here we demonstrate that mice with an intestinal epithelial cell (IEC)-specific deletion of the epigenome-modifying enzyme histone deacetylase 3 (HDAC3(ΔIEC) mice) exhibited extensive dysregulation of IEC-intrinsic gene expression, including decreased basal expression of genes associated with antimicrobial defence.
Epigenetics and Autism.
Washington, D.C., United States. In Autism Res Treat, Dec 2012
HDAC1 inhibition can overactivate mRNA transcription, a putative mechanism for the increased number of cerebral cortical columns and local frontal cortex hyperactivity in autistic individuals.
Characterization of pea histone deacetylases.
Burjassot, Spain. In Plant Mol Biol, 1988
Three enzyme fractions with histone deacetylase activity (HD0, HD1 and HD2) have been partially purified from pea (Pisum sativum) embryonic axes.