Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster.
In PLoS ONE, 2005
... weight fibroblast growth factor (lo-FGF Santa Cruz Biotechnology), HO-1 (Stressgen, Ann Arbor, MI, USA), cytochrome-c, HDAC5 (Cell Signaling, Danvers, MA, USA), HDAC1 ...
Keep-ING Balance: Tumor Suppression by Epigenetic Regulation.
Berlin, Germany. In Febs Lett, 13 Apr 2014
The ING (inhibitor of growth) proteins (ING1 - ING5) have emerged as a versatile family of growth regulators, phospholipid effectors, histone mark sensors and core components of HDAC1/2 - and several HAT chromatin-modifying complexes.
Epigenetic control of epithelial-mesenchymal-transition in human cancer.
Salzburg, Austria. In Mol Clin Oncol, 2013
As several approaches of epigenetic therapy are already under clinical evaluation, including inhibitors of DNA methyl transferase and histone deacetylase, targeting the epigenetic regulation of EMT may represent a promising therapeutic option in the future.
Micro-RNA-632 downregulates DNAJB6 in breast cancer.
Mobile, United States. In Lab Invest, 2012
miR-632 is a potentially important epigenetic regulator of DNAJB6, which contributes to the downregulation of DNAJB6 and plays a supportive role in malignant progression