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CYP1A1, p24, CYP1A2, p24 antigen
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011] (from
Zanger Ulrich M. et al., In Frontiers in Pharmacology, 2008
... For absolute quantification, a standard curve was generated by coanalyzing 250–4000 fmol of recombinantly expressed CYP1A2 in insect cell membranes (Becton Dickinson Gentest, Heidelberg, Germany) in ...
Müller et al., Toronto, Canada. In Expert Opin Drug Metab Toxicol, Nov 2015
Pharmacokinetic genes explored primarily include CYP1A2, while pharmacodynamic genes consisted of traditional pharmacogenetic targets such as brain-derived neurotrophic factor as well novel mitochondrial genes, NDUFS-1 and translocator protein.
Silva et al., São Paulo, Brazil. In Genet Mol Res, 2014
The aim of this case-control study was to obtain a comprehensive panel of genetic polymorphisms present only in genes (cytochrome P-450 1A1 - CYP1A1 and catechol-O-methyl transferase - COMT) within the metabolic pathway of sex steroids and determine their possible associations with the presence or absence of cervical cancer.
Yisikandaer et al., Ürümqi, China. In Genet Mol Res, 2014
This study aimed to investigate the correlation of CYP1A1 and GSTM1 gene polymorphisms and environmental factors to familial aggregation of esophageal cancer (EC) among the Kazakh ethnic group in Xinjiang.
Appay et al., Cardiff, United Kingdom. In Immunity, 2013
Here, we investigated protective HIV-1-specific CD8+ T cell responses directed against the immunodominant p24 Gag-derived epitope KK10 (KRWIILGLNK263-272) presented by human leukocyte antigen (HLA)-B∗2705.
El-Sohemy et al., Toronto, Canada. In Am J Clin Nutr, 2012
genetic association studies in a Costa Rican population: Previous associations observed between an SNP in CYP1A2 (rs2470893) and caffeine/coffee consumption in European populations are also observed in an ethnically distinct Costa Rican population.
Rawlins Richard G. et al., In ISRN Obstetrics and Gynecology, 2004
... for immune complex disruption and ELISA determination of HIV-1 antigen p24 (hereafter referred to as p24) levels, and real-time reverse transcription-PCR determination of HIV-1 RNA were obtained in kit forms from PerkinElmer Life Sciences, Inc ...
... Viral titre was measured by HIV-1 p24 antigen quantification.Mouse anti-gB and anti-gD monoclonal antibodies (Mabs) were obtained from Serotec (Oxford, UK) and Advanced Biotechnologies Incorporated, respectively ...