Analgesic and Anti-Inflammatory Activities of Rosa taiwanensis Nakai in Mice.
Taiwan. In J Med Food, 10 Jan 2015
The anti-inflammatory mechanism of RTEtOH was examined by measuring the levels of cyclooxygenase-2 (COX-2), nitric oxide (NO), tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and malondialdehyde (MDA) in the paw edema tissue and the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GRd) in the liver tissue.
Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance.
Houston, United States. In Nature, 03 Jan 2015
In vivo administration of the cyclooxygenase-2 (COX2) inhibitor celecoxib effectively abolishes a PGE2- and COX2-mediated wound response gene signature, and attenuates progressive manifestation of chemoresistance in xenograft tumours, including primary xenografts derived from a patient who was resistant to chemotherapy.
Nonsteroidal Antiinflammatory Drugs, Cyclooxygenase-2, and the Kidneys.
Davenport, United States. In Prim Care, 31 Dec 2014
UNLABELLED: Nonsteroidal antiinflammatory drugs (NSAIDs) are one of the most commonly used classes of medications in the world, which function by inhibiting the cyclooxygenase (COX) enzymes and downregulating the inflammatory pathway.
Endocannabinoid Metabolism by Cytochrome P450 Monooxygenases.
Urbana, United States. In Prostaglandins Other Lipid Mediat, 24 Dec 2014
Both AEA and 2-AG are also substrates for the eicosanoid-synthesizing pathways, namely, certain cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes.
The isoprostanes-25 years later.
Nashville, United States. In Biochim Biophys Acta, 30 Nov 2014
UNLABELLED: Isoprostanes (IsoPs) are prostaglandin-like molecules generated independent of the cyclooxygenase (COX) by the free radical-induced peroxidation of arachidonic acid.
Hepatic encephalopathy: effects of liver failure on brain function.
More papers using
Valencia, Spain. In Nat Rev Neurosci, Dec 2013
New therapeutic strategies acting on specific targets in the brain (phosphodiesterase 5, type A GABA receptors, cyclooxygenase and mitogen-activated protein kinase p38) have been shown to restore cognitive and motor function in animal models of chronic HE, and NMDA receptor antagonists have been shown to increase survival in acute liver failure.