Oral leukoplakia - To treat or not to treat.
Copenhagen, Denmark. In Oral Dis, Feb 2016
The systemic therapies tested so far include retinoids, extracts of green tea, inhibitors of cyclooxygenase-2 and of epidermal growth factor, and peroxisome proliferator activated receptor-γ agonists (William, 2012), but there is no generally approved standard systemic therapy regimen so far (William, 2012).
Factors affecting platinum sensitivity in cervical cancer.
Tokyo, Japan. In Oncol Lett, Dec 2015
Each specimen was assessed for immunohistochemical expression of Ki-67, p53, B-cell lymphoma-2 (Bcl-2), Bcl-2-associated X protein (Bax), cleaved caspase-3, cyclooxygenase-2 (COX-2), and excision repair cross-complementation group 1 (ERCC1).
Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance.
More papers using
Houston, United States. In Nature, Feb 2015
In vivo administration of the cyclooxygenase-2 (COX2) inhibitor celecoxib effectively abolishes a PGE2- and COX2-mediated wound response gene signature, and attenuates progressive manifestation of chemoresistance in xenograft tumours, including primary xenografts derived from a patient who was resistant to chemotherapy.