The role of gastrokine 1 in gastric cancer.
Seoul, South Korea. In J Gastric Cancer, Sep 2014
In the stomach, GKN1 is involved in gastric mucosal inflammation by regulating cytokine production, the nuclear factor-κB signaling pathway, and cyclooxygenase-2 expression.
COX-2 Inhibitors and Gastric Cancer.
Nanning, China. In Gastroenterol Res Pract, Dec 2013
The evidence that cyclooxygenase-2 (COX-2) is upregulated and plays an important role in carcinogenesis of gastric cancer has triggered the topic of COX-2 inhibitors as chemopreventive agents for gastric cancer.
Hepatic encephalopathy: effects of liver failure on brain function.
More papers using
Valencia, Spain. In Nat Rev Neurosci, Dec 2013
New therapeutic strategies acting on specific targets in the brain (phosphodiesterase 5, type A GABA receptors, cyclooxygenase and mitogen-activated protein kinase p38) have been shown to restore cognitive and motor function in animal models of chronic HE, and NMDA receptor antagonists have been shown to increase survival in acute liver failure.