Association between cell cycle gene transcription and tumor size in oral squamous cell carcinoma.
Belo Horizonte, Brazil. In Tumour Biol, Dec 2015
Among these genes, 13 reached statistical significance: ANAPC4, CUL1, SUMO1, KPNA2, MAD2L2, CCNG2, E2F4, NBN, CUL2, PCNA, TFDP1, KNTC1, and ATR.
Phosphoinositide 3-kinase and Forkhead, a switch for cell division.
Madrid, Spain. In Biochem Soc Trans, 2004
Another mechanisms by which PI3K and its downstream effector protein kinase B regulate cell cycle entry is by inactivation of the FOXO (Forkhead Box, subgroup O) transcription factors, which induce expression of quiescence genes such as those encoding p27(kip), p130 and cyclin G2.