Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer.
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Houston, United States. In Gastroenterol Res Pract, Dec 2014
The anticancer activity of ginger is attributed to its ability to modulate several signaling molecules like NF-κB, STAT3, MAPK, PI3K, ERK1/2, Akt, TNF-α, COX-2, cyclin D1, cdk, MMP-9, survivin, cIAP-1, XIAP, Bcl-2, caspases, and other cell growth regulatory proteins.
Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation
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