Alteration of cell cycle progression by Sindbis virus infection.
Chiba, Japan. In Biochem Biophys Res Commun, 11 Jun 2015
SINV infection affected the expression of several cell cycle regulators (CDK4, CDK6, cyclin E, p21, cyclin A and cyclin B) in HeLa cells and caused HeLa cells to accumulate in S phase during the early stage of infection.
Control of sleep by cyclin A and its regulator.
New York City, United States. In Science, 2012
We show that cyclin A (CycA) and regulator of cyclin A1, essential cell cycle factors, function in postmitotic neurons to promote sleep in Drosophila melanogaster.
How APC/C-Cdc20 changes its substrate specificity in mitosis.
Cambridge, United Kingdom. In Nat Cell Biol, 2011
Cdc20 requires APC3 and APC8 to bind and activate the APC/C when the spindle assembly checkpoint is satisfied, but only APC8 when active, and APC10 is crucial for the destruction of cyclin B1 and securin, but not cyclin A