Genetics of Hearing Loss-Nonsyndromic.
Stanford, United States. In Otolaryngol Clin North Am, 31 Dec 2015
Although AR nonsyndromic SNHL is most commonly caused by GJB2 and SLC26A4, there is no single gene that accounts for any significant proportion of AD SNHL.
Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment.
Ames, United States. In Heredity (edinb), 11 Dec 2015
In particular, selection signatures spanning several genes that directly or indirectly influenced traits for adaptation to hot arid environments, such as thermo-tolerance (melanogenesis) (FGF2, GNAI3, PLCB1), body size and development (BMP2, BMP4, GJA3, GJB2), energy and digestive metabolism (MYH, TRHDE, ALDH1A3), and nervous and autoimmune response (GRIA1, IL2, IL7, IL21, IL1R1) were identified.
PPARγ: Welcoming the New Kid on the CML Stem Cell Block.
San Francisco, United States. In Cancer Cell, 12 Nov 2015
Recently, chronic myeloid leukemia (CML) patients already responding to treatment showed improved molecular responses with pioglitazone, presumably through PPARγ activation and CML stem cell eradication.