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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

SCY1-like 2

CVAK104, coated vesicle-associated kinase of 104 kDa
Top mentioned proteins: AP-1, beta2, p15, Transferrin, CLint
Papers on CVAK104
SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.
Pelletier et al., Memphis, United States. In J Neurosci, Aug 2015
Here we show that the coated vesicle-associated kinase SCYL2/CVAK104 plays a critical role for the normal functioning of the nervous system and for suppressing excitotoxicity in the developing hippocampus.
A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).
Miki et al., Suita, Japan. In J Biol Chem, 2009
Studies identify CVAK104 as a novel binding partner of Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5.
CVAK104 is a novel regulator of clathrin-mediated SNARE sorting.
Robinson et al., Cambridge, United Kingdom. In Traffic, 2007
CVAK104 is an evolutionarily conserved protein involved in SNARE sorting that is essential for normal embryonic development
Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network.
Ungewickell et al., Hannover, Germany. In Mol Biol Cell, 2006
Together, our data suggest a function for CVAK104 in clathrin-dependent pathways between the trans-Golgi network and the endosomal system.
CVAK104 is a novel poly-L-lysine-stimulated kinase that targets the beta2-subunit of AP2.
Schmid et al., Minneapolis, United States. In J Biol Chem, 2005
CVAK104 binds ATP and functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosphorylation and phosphorylating the beta2-adaptin subunit of AP2.
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