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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

SCY1-like 2

CVAK104, coated vesicle-associated kinase of 104 kDa
Top mentioned proteins: AP-1, beta2, p15, Transferrin, CLint
Papers on CVAK104
SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.
New
Pelletier et al., Memphis, United States. In J Neurosci, Aug 2015
Here we show that the coated vesicle-associated kinase SCYL2/CVAK104 plays a critical role for the normal functioning of the nervous system and for suppressing excitotoxicity in the developing hippocampus.
A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).
GeneRIF
Miki et al., Suita, Japan. In J Biol Chem, 2009
Studies identify CVAK104 as a novel binding partner of Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5.
CVAK104 is a novel regulator of clathrin-mediated SNARE sorting.
GeneRIF
Robinson et al., Cambridge, United Kingdom. In Traffic, 2007
CVAK104 is an evolutionarily conserved protein involved in SNARE sorting that is essential for normal embryonic development
Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network.
GeneRIF
Ungewickell et al., Hannover, Germany. In Mol Biol Cell, 2006
Together, our data suggest a function for CVAK104 in clathrin-dependent pathways between the trans-Golgi network and the endosomal system.
CVAK104 is a novel poly-L-lysine-stimulated kinase that targets the beta2-subunit of AP2.
GeneRIF
Schmid et al., Minneapolis, United States. In J Biol Chem, 2005
CVAK104 binds ATP and functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosphorylation and phosphorylating the beta2-adaptin subunit of AP2.
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