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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CTR9 Ctr9p

Ctr9, T-SP, SH2 domain-binding protein, CDP1
CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Paf1, POLYMERASE, Rdl, CAN, V1a
Papers on Ctr9
Integrative analysis of genome-wide association studies and gene expression profiles identified candidate genes for osteoporosis in Kashin-Beck disease patients.
Zhang et al., Xi'an, China. In Osteoporos Int, Nov 2015
GWAS meta-analysis identified six candidate genes with pleiotropic effects, including PDGFD, SOX5, DPYD, CTR9, SPP1, and COL4A1.
Using the synergism strategy for highly sensitive and specific electrochemical sensing of Streptococcus pneumoniae Lyt-1 gene sequence.
He et al., Harbin, China. In Anal Chim Acta, Aug 2015
With the help of the interaction mode of capture probe-target-signal probe (CP-T-SP), an electrochemical sensing method based on the synergism strategy of dual-hybridized signaling probes modified with 6 MB (methylene blue), background suppression and large surface area Au electrode is developed for the detection of Streptococcus pneumoniae (S. pneumoniae) Lyt-1 gene sequence.
A highly sensitive and specific electrochemical sensing method for robust detection of Escherichia coli lac Z gene sequence.
He et al., Harbin, China. In Biosens Bioelectron, Jul 2015
Based on the interaction mode of capture probe-target-signal probe (CP-T-SP), a simple but efficient electrochemical sensing method is developed for robust detection of Escherichia coli (E.
Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.
Yoo et al., South Korea. In Plos One, 2014
PAFc is an evolutionarily conserved, multi-protein complex comprising PAF1, CDC73, CTR9, LEO1, yRTF1 and, in humans, hSKI8.
Transcriptional regulator CTR9 inhibits Th17 differentiation via repression of IL-17 expression.
Yoo et al., South Korea. In J Immunol, 2014
In this study, we show that CTR9, a component of PAF complex, functions as a repressor of Th17 differentiation.
Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour.
Rahman et al., London, United Kingdom. In Nat Commun, 2013
Here we identify inactivating CTR9 mutations in 3 of 35 Wilms tumour families, through exome and Sanger sequencing.
CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.
Mager et al., Amherst Center, United States. In Dev Biol, 2013
Here we report that two members of the RNA polymerase II associated factor, homolog (Saccharomyces cerevisiae) complex (PAF1 complex) components, Ctr9 and Rtf1, are required during mammalian preimplantation development.
MMAPPR: mutation mapping analysis pipeline for pooled RNA-seq.
Yost et al., Salt Lake City, United States. In Genome Res, 2013
We tested MMAPPR on two known mutant lines in zebrafish, nkx2.5 and tbx1, and used it to map two novel ENU-induced cardiovascular mutants, with mutations found in the ctr9 and cds2 genes.
Expression profile of host restriction factors in HIV-1 elite controllers.
Pillai et al., San Francisco, United States. In Retrovirology, 2012
APOBEC3C, APOBEC3D, CTR9, TRIM26, and TRIM32 were elevated in elite controllers with respect to ART-suppressed individuals, while levels were comparable to uninfected individuals and non-controllers.
CTR9, a component of PAF complex, controls elongation block at the c-Fos locus via signal-dependent regulation of chromatin-bound NELF dissociation.
Yoo et al., South Korea. In Plos One, 2012
When CTR9, a component of PAFc, was depleted, higher levels of serine 5-phosphorylated or serine 2-phosphorylated forms of RNA Polymerase II were associated with the unstimulated c-Fos locus.
Proteome analysis of a CTR9 deficient yeast strain suggests that Ctr9 has function(s) independent of the Paf1 complex.
Guieysse-Peugeot et al., Bordeaux, France. In Biochim Biophys Acta, 2012
The Ctr9 protein is a member of the Paf1 complex implicated in multiple functions: transcription initiation and elongation by RNA pol II, RNA processing and histone modifications.
Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.
Sada et al., Fukui, Japan. In Genes Cells, 2011
Previously, a linker for activation of T cells (LAT) was identified as one of the 3BP2 SH2 domain-binding protein.
Comparison of oogenesis and sex steroid profiles between twice and once annually spawning of rainbow trout females (Oncorhynchus mykiss).
Araneda et al., Santiago, Chile. In Scientificworldjournal, 2011
This study compares the gonadosomatic index (GSI), oocyte growth (OG), gonadal histology, and plasma level concentrations of sex hormones (estradiol-17β (E2) and vitellogenin (V)) of twice-spawning (T-SP) and once-spawning (O-SP) females of rainbow trout throughout the additional and the normal reproductive cycle, respectively.
Depletion of trypanosome CTR9 leads to gene expression defects.
Clayton et al., Heidelberg, Germany. In Plos One, 2011
The Paf complex of Opisthokonts and plants contains at least five subunits: Paf1, Cdc73, Rtf1, Ctr9, and Leo1.
Assessing swallowing disorders online: a pilot telerehabilitation study.
Russell et al., Brisbane, Australia. In Telemed J E Health, 2011
Dysphagia was assessed simultaneously by a face-to-face (FTF) and telerehabilitation speech pathologist (T-SP).
The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.
Hess et al., Ann Arbor, United States. In Cancer Cell, 2010
MLL interacts directly with the polymerase associated factor complex (PAFc) via Paf1 and CTR9. PAFc augments MLL and MLL-AF9 mediated transcriptional activation of Hoxa9 and their interaction is essential for leukemogenesis.
The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II.
Desiderio et al., Baltimore, United States. In Bmc Mol Biol, 2007
depletion of the Ctr9 or Paf1 component of the Paf1 complex delays the loss of histones from the GAL1 gene upon induction.
hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions.
Yoo et al., South Korea. In J Biol Chem, 2007
CTR9 participates in the transcription of IL-6-responsive genes through the regulation of DNA association of STAT3 and modification of histone methylation
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