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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Solute carrier family 44, member 1

CTL1, choline transporter-like protein 1
may be a choline transporter for a specific subset of cholinergic neurons [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CTL2, ACID, V1a, CAN, OCT
Papers on CTL1
Functional expression of choline transporter like-protein 1 (CTL1) and CTL2 in human brain microvascular endothelial cells.
Inazu et al., Tokyo, Japan. In Neurochem Int, Jan 2016
Choline transporter-like protein 1 (CTL1) and CTL2 mRNA were highly expressed, while mRNA for high-affinity choline transporter 1 (CHT1) and organic cation transporters (OCTs) were not expressed in hBMECs.
Identification of immunodominant antigens for the laboratory diagnosis of toxocariasis.
Hotez et al., Houston, United States. In Trop Med Int Health, Dec 2015
The first CTL (Tc-CTL-1) is the same as TES-32, previously identified as a major immunodominant component of TES; the second CTL (Tc-CTL-2) is a novel C-type lectin sharing 83% amino acid sequence identity within the functional domain of Tc-CTL-1.
Characterization of choline transporters in the human placenta over gestation.
Winn et al., Aurora, United States. In Placenta, Dec 2015
METHODS: We analyzed CTL1 and -2 expression over gestation in human placental biopsies from 6 to 40 weeks gestation (n = 6-10 per gestational window) by immunoblot analysis.
Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Hohenester et al., London, United Kingdom. In Structure, Dec 2015
The L-shaped arrangement of these domains creates a shallow trench spanning the FN2 and CTL1 domains, which was shown by mutagenesis to bind triple-helical and denatured collagen.
Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters.
Kummer et al., Gießen, Germany. In Int Immunopharmacol, Nov 2015
To evaluate the cellular sources of non-quantal ACh release in the trachea, expression of low-affinity choline transporter-like family (CTL1-5) was evaluated by RT-PCR analysis.
Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26.
Handali et al., Houston, United States. In Plos Negl Trop Dis, Oct 2015
Three predominant immunoreactive proteins were found in the TES; all three had been previously described in the literature: Tc-CTL-1, Tc-TES-26, and Tc-MUC-3.
Monocyte Chemoattractant Protein-Induced Protein 1 Overexpression Modulates Transcriptome, Including MicroRNA, in Human Neuroblastoma Cells.
Rokita et al., Kraków, Poland. In J Cell Biochem, Sep 2015
The choline transporter, CTL1, encoded by the SLC44A1 gene, was significantly repressed at the specific mRNA and protein levels and most importantly this translated into a decreased choline transport in MCPIP1-overexpressing cells.
Molecular and functional characterization of choline transporter in the human trophoblastic cell line JEG-3 cells.
Inazu et al., Tokyo, Japan. In Placenta, Jun 2015
Choline transporter-like protein 1 (CTL1) and CTL2 mRNA and protein were highly expressed in JEG-3 cells and were localized to the plasma membrane.
Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts.
Bakovic et al., Guelph, Canada. In Faseb J, May 2015
The choline transporter-like protein 1/solute carrier 44A1 (CTL1/SLC44A1) and mRNA expression were 2-3 times lower in POTS fibroblasts, and choline uptake was reduced 60% (P < 0.05).
Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis.
Lips et al., Gießen, Germany. In Cell Tissue Res, Feb 2015
The expression of CTL1 and CTL2 was localized in synovial macrophages and fibroblasts.
Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism.
Bhujwalla et al., Baltimore, United States. In Clin Cancer Res, Feb 2015
Molecular characterization revealed overexpression of choline kinase (Chk)-α, choline transporter 1 (CHT1), and choline transporter-like protein 1 (CTL1) in the PDAC cell lines and tumors.
Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells.
Hashimoto et al., Toyama, Japan. In Biopharm Drug Dispos, 2014
The mRNA of choline transporter-like proteins (CTLs) was expressed significantly in LS180 cells, and the rank order was CTL1 > CTL4 > CTL3 > CTL2 > CTL5.
Palmitic acid and oleic acid differentially regulate choline transporter-like 1 levels and glycerolipid metabolism in skeletal muscle cells.
Bakovic et al., Guelph, Canada. In Lipids, 2014
Here we elucidate the mechanism of how palmitic acid (PAM) and oleic acid (OLA) regulate choline transporter-like protein 1 (CTL1/SLC44A1) function.
The ubiquitous choline transporter SLC44A1.
Bakovic et al., Albuquerque, United States. In Cent Nerv Syst Agents Med Chem, 2012
The solute carrier 44A1 (SLC44A1), also referred to as choline transporter-like protein 1 (CTL1), is a recently discovered choline transporter with an intermediate affinity for choline; this transport is Na(+)-independent and sensitive to inhibition by the drug hemicholinium-3.
Chitinase-like1/pom-pom1 and its homolog CTL2 are glucan-interacting proteins important for cellulose biosynthesis in Arabidopsis.
Persson et al., Potsdam, Germany. In Plant Cell, 2012
CTL1 affects primary wall cellulose deposition. CTL1 and CTL2 influence the cellulose assembly and are involved in cross-linking of glucan-based polysaccharides.
Dissecting the role of CHITINASE-LIKE1 in nitrate-dependent changes in root architecture.
Bush et al., Brussels, Belgium. In Plant Physiol, 2011
The spatial pattern of CTL1 expression was mainly in the root and root tips during seedling development and that the protein localized to the cell wall.
Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis.
Matsumiya et al., Tokyo, Japan. In Neurochem Int, 2011
CTL1 is expressed in both SH-SY5Y and LA-N-2 cells and is responsible for choline uptake that relies on a directed hydrogen ion gradient as a driving force.
Chitinase-like protein CTL1 plays a role in altering root system architecture in response to multiple environmental conditions.
Bush et al., Fort Collins, United States. In Plant Physiol, 2010
AtCTL1 plays a role in plant growth and development wherein has a constitutive effect on cell wall synthesis and cell elongation, and its function is modulated by environmental stimuli, such as high nitrate concentration, that alter organ morphology.
Involvement of choline transporter-like proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synthesis via increased choline uptake.
Tamai et al., Kanazawa, Japan. In Biol Pharm Bull, 2009
In conclusion, choline transport in A549 cells is increased by treatment with DEX, and the increase is mediated by induction of functional choline transporters CTL1 and CTL2.
Choline transport for phospholipid synthesis.
Bakovic et al., Guelph, Canada. In Exp Biol Med (maywood), 2006
They include (i) polyspecific organic cation transporters (OCTs) with low affinity for choline, (ii) high-affinity choline transporters (CHT1s), and (iii) intermediate-affinity choline transporter-like (CTL1) proteins.
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