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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Regulator of calcineurin 3

Csp3, DSCR1L2, RCAN3, Down syndrome critical region gene 1-like 2, RCN3
Top mentioned proteins: Csp2, CAN, PrP, ACID, V1a
Papers on Csp3
Bu4NI Catalyzed C-N Bond Formation via Cross-Dehydrogenative Coupling of Aryl Ethers (Csp3-H) and Tetrazoles (N-H).
New
Patel et al., North Guwāhāti, India. In Org Lett, Dec 2015
Intermolecular C-N bond formations via cross-dehydrogenative coupling (CDC) of aryl ethers and tetrazoles have been developed under a metal-free condition.
Lithium Aluminate Complexes and Alumoles from 1,4-Dilithio-1,3-Butadienes and AlEt2Cl.
New
Xi et al., Beijing, China. In Inorg Chem, Dec 2015
The structure of the lithium aluminate complex 2-TMEDA showed that the Al atom adopted a tetra-coordinated mode bonded with two butadienyl Csp2 atoms and two ethyl Csp3 atoms.
Silicates as Latent Alkyl Radical Precursors: Visible-Light Photocatalytic Oxidation of Hypervalent Bis-Catecholato Silicon Compounds.
New
Fensterbank et al., Paris, France. In Angew Chem Int Ed Engl, Oct 2015
This oxidative photocatalyzed process can be efficiently merged with nickel-catalyzed Csp2-Csp3 cross-coupling reactions.
A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer.
New
Pérez-Riba et al., Barcelona, Spain. In Carcinogenesis, Jul 2015
In this work, we report that the overexpression of RCAN3 dramatically inhibits tumor growth and tumor angiogenesis in an orthotopic human breast cancer model.
Modular Approach to Reductive C(sp2)-H and C(sp3)-H Silylation of Carboxylic Acid Derivatives through Single-Pot, Sequential Transition Metal Catalysis.
New
Jeon et al., Arlington, United States. In J Org Chem, Jun 2015
We report a modular approach to catalytic reductive Csp2-H and Csp3-H silylation of carboxylic acid derivatives encompassing esters, ketones, and aldehydes.
RCAN 1 and 3 proteins regulate thymic positive selection.
New
Pérez-Riba et al., Barcelona, Spain. In Biochem Biophys Res Commun, Jun 2015
Overexpression of human RCAN3 and RCAN1 can modulate T cell development by increasing positive selection-related surface markers, as well as the "Erk(hi) competence state" in double positive thymocytes, a characteristic molecular signature of positive selection, without affecting CN activity.
Efficient Synthesis of β-CF3/SCF3-Substituted Carbonyls via Copper-Catalyzed Electrophilic Ring-Opening Cross-Coupling of Cyclopropanols.
New
Dai et al., West Lafayette, United States. In Org Lett, Jun 2015
The first copper-catalyzed ring-opening electrophilic trifluoromethylation and trifluoromethylthiolation of cyclopropanols to form Csp3-CF3 and Csp3-SCF3 bonds have been realized.
Inhibiting Rho kinase 2 reduces memory dysfunction in adult rats exposed to sevoflurane at postnatal days 7-9.
New
Liao et al., Changsha, China. In Biomed Rep, May 2015
The protein levels of RhoA, ROCK2 and cleaved caspase-3 (Cl-Csp3) in the adult hippocampus were assessed by western blot analysis.
Cobalt-catalyzed cross-dehydrogenative coupling reaction in water by visible light.
New
Wu et al., Beijing, China. In Org Lett, Mar 2015
The desired cross-coupling C-C bonds that involve Csp3 with Csp, Csp2, and Csp3, respectively, were achieved exclusively in high yields without formation of any other byproduct.
Nickel-catalyzed selective oxidative radical cross-coupling: an effective strategy for inert Csp3-H functionalization.
New
Lei et al., Wuhan, China. In Org Lett, Mar 2015
An effective strategy for inert Csp(3)-H functionalization through nickel-catalyzed selective radical cross-couplings was demonstrated.
Orchestrated triple C-H activation reactions using two directing groups: rapid assembly of complex pyrazoles.
New
Yu et al., Los Angeles, United States. In Angew Chem Int Ed Engl, Mar 2015
Pyrazole as a relatively weak coordinating group is shown to direct Csp3-H activation for the first time.
Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules.
New
Mata et al., Rosario, Argentina. In Acs Comb Sci, Mar 2015
It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium-catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages.
Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism.
Impact
Siegel et al., Austin, United States. In Nature, 2013
Although the reaction proceeds through a radical mechanism, aromatic C-H bonds are selectively oxidized in preference to activated Csp3-H bonds.
Human RCAN3 gene expression and cell growth in endothelial cells.
GeneRIF
Perretti et al., Bologna, Italy. In Int J Mol Med, 2010
Data shows RCAN3 inhibits HUVEC proliferation both basally and under VEGF or phorbol 12-myristate 13-acetate-stimulated conditions, however it does not modulate gene expression of the chosen inflammatory genes.
Complexity of bidirectional transcription and alternative splicing at human RCAN3 locus.
GeneRIF
Canaider et al., Bologna, Italy. In Plos One, 2010
Studies indicate that RCAN3 is composed of a multigene system that includes at least 21 alternative spliced isoforms.
Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway.
GeneRIF
Jabbour et al., Edinburgh, United Kingdom. In Biochim Biophys Acta, 2009
our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression
The rapidly expanding CREC protein family: members, localization, function, and role in disease.
Review
Honoré, Århus, Denmark. In Bioessays, 2009
The CREC family of low affinity, Ca2+-binding, multiple EF-hand proteins are encoded by five genes, RCN1, RCN2, RCN3, SDF4, and CALU, resulting in reticulocalbin, ER Ca2+-binding protein of 55 kDa (ERC-55), reticulocalbin-3, Ca2+-binding protein of 45 kDa (Cab45), and calumenin.
Identification and analysis of human RCAN3 (DSCR1L2) mRNA and protein isoforms.
GeneRIF
Strippoli et al., Bologna, Italy. In Gene, 2008
The interaction between TNNI3 and the new R variants of RCAN3, RCAN3-2,3,5 and RCAN3-2,4,5, is reported.
Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain.
GeneRIF
Arbonés et al., Barcelona, Spain. In Eur J Neurosci, 2007
the adult mice, RCAN3 was mainly expressed in the neuropil throughout the brain.
Topological analyses and bond characterization of 1,3,5,7-tetra-tert-butyl-s-indacene: a weak Csp3-H...H-Csp2-type dihydrogen interaction.
Impact
Wang et al., Taipei, Taiwan. In Acta Crystallogr A, 2004
Topological analyses of experimental and theoretical calculated electron densities of 1,3,5,7-tetra-tert-butyl-s-indacene provide bond characterizations of the chemical bond and of the pi-delocalization.
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