Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.
Montpellier, France. In Curr Protein Pept Sci, 2013
In eukaryotes, MPN domain-containing proteins are commonly found in association with other molecules in large protein complexes, where examples comprise; the 26S proteasome and the COP9 (Constitutive photomorphogenesis 9) signalosome complexes, including the MPN subunits, POH1 and Mov34, CSN5 and CSN6, respectively.
Roles of COP9 signalosome in cancer.
Houston, United States. In Cell Cycle, 2011
Among the CSN subunits, CSN5 and CSN6 are the only two that each contain an MPN (Mpr1p and Pad1p N-terminal) domain.