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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CUB and Sushi multiple domains 3

Top mentioned proteins: HAD, CAN, p53, KRAS, EGFR
Papers on CSMD3
Next generation sequencing in synovial sarcoma reveals novel gene mutations.
Versleijen-Jonkers et al., Nijmegen, Netherlands. In Oncotarget, Nov 2015
Additional mutations were detected in RNF213, SEPT9, KDR, CSMD3, MLH1 and ERBB4.
The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing.
Siebert et al., Kiel, Germany. In Leukemia, Mar 2015
Together with mutations affecting CSMD2, CSMD3, and PTPRD, these findings may suggest that alterations in genes having a role in CNS development may facilitate diffuse large B-cell lymphoma manifestation in the CNS.
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes.
Aravindan et al., Oklahoma City, United States. In Bmc Cancer, 2014
Array CGH analysis of individual clones of MSDACs revealed genetic alterations in chromosomes 1, 7, 8, and 22, corresponding to a gain in the copy numbers of LOC100288142, CD1C, CFHR3, FOXP2, MDFIC, RALYL, CSMD3, SAMD12-AS1, and MAL2, and a loss in ADAM5, LOC400927, APOBEC3B, RPL3, MGAT3, SLC25A17, EP300, L3MBTL2, SERHL, POLDIP3, A4GALT, and TTLL1.
Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.
Song et al., Shenyang, China. In Tumour Biol, 2014
In this work, we aimed to study the protein and mRNA levels of the CSMD1, CSMD2, and CSMD3 and evaluate their prognostic importance in colorectal cancer.
Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers.
Bang et al., Seoul, South Korea. In Genome Med, 2013
These included targetable genes involved in PI3K/mTOR signaling (TSC1, PIK3CA, AKT2) and receptor tyrosine kinase signaling (ERBB4) and genes not previously highlighted in lung adenocarcinomas, such as SETD2 and PBRM1 (chromatin remodeling), CHEK2 and CDC27 (cell cycle), CUL3 and SOD2 (oxidative stress), and CSMD3 and TFG (immune response).
An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Ashktorab et al., Long Branch, United States. In Plos One, 2013
Most deletions were noted for ADAM29, CHL1, CSMD3, FBXW7, GALNS, MMP2, NF1, PRKD1, SMAD4 and TP53.
A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia.
Roug et al., Århus, Denmark. In Leuk Res Rep, 2013
encompassing various cancer relevant genes of which RAD21 and CSMD3 are of particular interest.
Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease.
Kim et al., Boston, United States. In Embo Mol Med, 2013
We discovered that urine proteomes of patients with KD, but not those with mimicking conditions, were enriched for markers of cellular injury such as filamin and talin, immune regulators such as complement regulator CSMD3, immune pattern recognition receptor muclin, and immune cytokine protease meprin A. Significant elevations of filamin C and meprin A were detected in both the serum and urine in two independent cohorts of patients with KD, comprised of a total of 236 patients.
[Whole-genome messenger RNA profiling reveals genes involved in malignant progression of glioma].
Jiang et al., Beijing, China. In Zhonghua Yi Xue Za Zhi, 2013
Microarray data were validated by immunohistochemistry. RESULTS: Among all the detected genes, the genes up-regulated mostly in high-grade glioma were IGFBP-2, CKLF, PTTG1, OSTCL and PTTG2 while those down-regulated mostly SEC31, RRP7B, HOOK3, SNRPN and CSMD3.
NRXN1 deletions identified by array comparative genome hybridisation in a clinical case series - further understanding of the relevance of NRXN1 to neurodevelopmental disorders.
Ogilvie et al., London, United Kingdom. In J Mol Psychiatry, 2012
Five patients who had deletions in NRXN1 had a second CNV implicated in neurodevelopmental disorder: a CNTNAP2 and CSMD3 deletion in patients with exonic NRXN1 deletions, and a Williams-Beuren syndrome deletion and two 22q11.2
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.
You et al., Milwaukee, United States. In Carcinogenesis, 2012
Notably, a novel gene CSMD3 was identified as the second most frequently mutated gene (next to TP53) in lung cancer.
Somatic mutations and germline sequence variants in patients with familial colorectal cancer.
Aaltonen et al., Helsinki, Finland. In Int J Cancer, 2011
Nonsynonymous variants of CSMD3 is associated with familial colorectal cancer.
Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men.
Leach et al., San Antonio, United States. In Carcinogenesis, 2009
Single-nucleotide polymorphisms in CSMD3 is associated with prostate cancer risk in hispanic men.
Two patients with balanced translocations and autistic disorder: CSMD3 as a candidate gene for autism found in their common 8q23 breakpoint area.
Crisponi et al., Cagliari, Italy. In Eur J Hum Genet, 2008
Breakpoints on chromosomes 8 in both patients do not interrupt any known gene but both map in a region containing the CSMD3 gene, which thereby can be considered as a candidate for autistic spectrum disorders
Pronounced short stature in a girl with tricho-rhino-phalangeal syndrome II (TRPS II, Langer-Giedion syndrome) and growth hormone deficiency.
Lüdecke et al., Vienna, Austria. In Am J Med Genet A, 2005
CSMD3 is deleted in a subject with combined tricho-rhino-phalangeal syndrome II with mental retardation and growth hormone deficiency.
A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.
Shimizu et al., Tokyo, Japan. In Biochem Biophys Res Commun, 2003
CSMD3 encodes a protein with CUB and sushi multiple domains and is a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1
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