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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Myozenin 2

CSI, calsarcin-1
The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, fibrillin-1, AGE
Papers on CSI
Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression.
New
Miller et al., Atlanta, United States. In Mol Psychiatry, Feb 2016
Multivoxel chemical shift imaging (CSI) was used to explore creatine-normalized measures of other metabolites in basal ganglia.
Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State Inactivation.
New
Bähring et al., Hamburg, Germany. In Biophys J, Feb 2016
We studied the kinetics and structural determinants of closed-state inactivation (CSI) in Kv4.2 channels, considering a multistep process and the possibility that both intra- and intersubunit dynamic binding (i.e., loss and restoration of physical contact) may occur between the S4-S5 linker, including the initial S5 segment (S4S5), and the S6 gate.
Molecular cloning and characterization of Siamese crocodile (Crocodylus siamensis) copper, zinc superoxide dismutase (CSI-Cu,Zn-SOD) gene.
New
Srikulnath et al., Bangkok, Thailand. In Comp Biochem Physiol A Mol Integr Physiol, Jan 2016
A gene coding for Cu,Zn-SOD was cloned and characterized from Siamese crocodile (Crocodylus siamensis; CSI).
Reduced expression of MyHC slow isoform in rat soleus during unloading is accompanied by alterations of endogenous inhibitors of calcineurin/NFAT signaling pathway.
New
Shenkman et al., Moscow, Russia. In J Muscle Res Cell Motil, Dec 2015
The study was aimed to analyze the states of the myonuclear NFAT inhibitors calsarcin I (CSI) and calsarcin II (CSII) (also referred to as myozenin II and I) and GSK3β in rat soleus during hindlimb suspension (HS).
A canonical circuit for visual contextual integration explains induction effects across visual modalities.
New
Serre et al., In J Vis, Oct 2015
A large and disparate body of work in electrophysiology has shown the prevalence of such center-surround integration (CSI); however, we are still lacking a common unifying mechanism across visual modalities.
A phylogenomic and molecular markers based analysis of the phylum Chlamydiae: proposal to divide the class Chlamydiia into two orders, Chlamydiales and Parachlamydiales ord. nov., and emended description of the class Chlamydiia.
New
Adeolu et al., Hamilton, Canada. In Antonie Van Leeuwenhoek, Sep 2015
Importantly, 17 CSIs and 98 CSPs were found to be specific for the family Chlamydiaceae while another 3 CSI variants and 15 CSPs were specific for a grouping of the families Criblamydiaceae, Parachlamydiaceae, Simkaniaceae and Waddliaceae.
Inference of nonlinear gene regulatory networks through optimized ensemble of support vector regression and dynamic Bayesian networks.
New
Seker et al., In Conf Proc Ieee Eng Med Biol Soc, Aug 2015
Nonlinear modeling methods such as the S-systems and causal structure identification (CSI) have been proposed, but are known to be statistically inefficient and analytically intractable in high dimensions.
Microbiology of diabetic foot infections: from Louis Pasteur to 'crime scene investigation'.
Review
Lipsky et al., Genève, Switzerland. In Bmc Med, 2014
We herein review current knowledge on the microbiology of DFI, from standard culture methods to the current era of rapid and comprehensive 'crime scene investigation' (CSI) techniques.
Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum.
Driessen et al., Groningen, Netherlands. In Bmc Genomics, 2014
The high β-lactam titers of current strains is the result of a classical strain improvement program (CSI) starting with a wild-type like strain more than six decades ago.
Colony Size Affects the Efficacy of Bait Containing Chlorfluazuron Against the Fungus-Growing Termite Macrotermes gilvus (Blattodea: Termitidae).
Lee et al., George Town, Malaysia. In J Econ Entomol, 2014
Nevertheless, we do not deny the possibility of CSI bait eliminating or suppressing the higher termite if the test colonies could pick up adequate lethal dose by installing more bait stations and prolonging the baiting period.
Phylogeny and molecular signatures for the phylum Thermotogae and its subgroups.
Review
Bhandari et al., Hamilton, Canada. In Antonie Van Leeuwenhoek, 2011
Additionally, comprehensive analyses of protein sequences from Thermotogae genomes have identified >60 Conserved Signature Indels (CSI) that are specific for the Thermotogae phylum or its different subgroups.
Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.
GeneRIF
Miller et al., London, United Kingdom. In J Cell Sci, 2011
Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1.
Mechanisms of closed-state inactivation in voltage-gated ion channels.
Review
Covarrubias et al., Hamburg, Germany. In J Physiol, 2011
Inactivation may occur from the open state (open-state inactivation, OSI) at strongly depolarized membrane potentials, or from pre-open closed states (closed-state inactivation, CSI) at hyperpolarized and modestly depolarized membrane potentials.
Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles.
GeneRIF
Sonderegger et al., Zürich, Switzerland. In Proteomics, 2010
Immunoisolated calsyntenin-1 organelles from murine brain homogenates; determined their proteome by MS. Found calsyntenin-1 organelles are endowed with components of the endosomal trafficking machinery and contained the beta-amyloid precursor protein (APP).
Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy.
GeneRIF
Vondriska et al., Los Angeles, United States. In J Mol Cell Cardiol, 2010
analysis of post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy
Sequence analysis of myozenin 2 in 438 European patients with familial hypertrophic cardiomyopathy.
GeneRIF
Ozcelik et al., Berlin, Germany. In Med Sci Monit, 2008
MYOZ2 mutations are rare causes of familial familial hypertrophic cardiomyopathy.
Calsyntenins are secretory granule proteins in anterior pituitary gland and pancreatic islet alpha cells.
GeneRIF
Neubert et al., New York City, United States. In J Histochem Cytochem, 2008
Results indicate that calsyntenins function outside the nervous system and potentially are modulators of endocrine function.
Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
Review
Banerjee et al., Calcutta, India. In Med Res Rev, 2008
Using the crystal structure of the tubulin-DAMAcolchicine complex, a detailed discussion on the pharmacophore concept that explains the variation of affinity for different colchicine site inhibitors (CSI) has been discussed.
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress.
Impact
GeneRIF
Olson et al., Dallas, United States. In Nat Med, 2004
calsarcin-1 negatively modulates the functions of calcineurin.
Cyclooxygenase-2 inhibitors: do they have a role in emergency department prescribing?
Review
Wilton, Wellington, New Zealand. In Emerg Med Australas, 2004
Cyclooxygenase-2 selective inhibitors (COXIB or CSI) have been released with a fanfare as efficacious and safer alternatives to traditional non-steroidal anti-inflammatory drugs.
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