Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.
Kansas City, United States. In Immunol Res, Jan 2016
In each group of patients, CD3(-) ISP and DP thymocytes were subdivided into ISP1, ISP2, DP1, DP2, DP3, DP4, and DP5 developmental stages according to their expression of CD28, CD44, CD1a, CD7, CD45RO, and CD38.
Emerging small-molecule compounds for treatment of atopic dermatitis: a review.
Hradec Králové, Czech Republic. In Expert Opin Ther Pat, Nov 2015
These substances include compounds targeting the skin barrier (filaggrin production promoters, filaggrin breakdown products and compounds improving stratum corneum lipid barrier including pseudoceramides), anti-inflammatory compounds (PDE4/7 inhibitors, CRTH2 inhibitors, chemokine receptor antagonists, inhibitors of chymase and other) and compounds specifically targeting itch (TRP agonists, opioid ligands, serotonin 7 and histamine 4 antagonists).