Hypothalamic-Pituitary--Adrenal Axis-Feedback Control.
United States. In Compr Physiol, Aug 2015
Negative feedback control by corticosteroids limits pituitary secretion of corticotropin, ACTH, and hypothalamic secretion of corticotropin-releasing hormone, CRH, and vasopressin, AVP, resulting in regulation of both basal and stress-induced ACTH secretion.
Madagascar. In Unknown Journal, May 2015
Exogenous glucocorticoids cause decreased secretion of corticotropin-releasing hormone (CRH) and other adrenocorticotropic hormone (ACTH) secretagogues, such as arginine-vasopressin (AVP) and alter the function of higher brain centers that regulate their secretion.
Key role of CRF in the skin stress response system.
Memphis, United States. In Endocr Rev, 2013
The discovery of corticotropin-releasing factor (CRF) or CRH defining the upper regulatory arm of the hypothalamic-pituitary-adrenal (HPA) axis, along with the identification of the corresponding receptors (CRFRs 1 and 2), represents a milestone in our understanding of central mechanisms regulating body and local homeostasis.
Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit.
San Francisco, United States. In Endocr Rev, 2011
Recent studies employing modern technologies such as gene expression profiling and laser capture microdissection have revealed that development and/or function of the fetal adrenal cortex may be regulated by a panoply of molecules, including transcription factors, extracellular matrix components, locally produced growth factors, and placenta-derived CRH, in addition to the primary regulator, fetal pituitary ACTH.