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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

LUC7-like 3

CRA, CROP, O48
This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009] (from NCBI)
Top mentioned proteins: ACID, CIs, CAN, HAD, V1a
Papers on CRA
Metabolic Regulation and Coordination of the Metabolism in Bacteria in Response to a Variety of Growth Conditions.
Review
New
Shimizu, Iizuka, Japan. In Adv Biochem Eng Biotechnol, Dec 2015
The metabolism is controlled by both enzyme-level regulation and transcriptional regulation via transcription factors such as cAMP-Crp, Cra, Csr, Fis, PII(GlnB), NtrBC, CysB, PhoR/B, SoxR/S, Fur, MarR, ArcA/B, Fnr, NarX/L, RpoS, and (p)ppGpp for stringent response, where the timescales for enzyme-level and gene-level regulations are different.
Anti-Outer membrane protein C antibodies in colorectal neoplasia.
New
Bures et al., Hradec Králové, Czech Republic. In Folia Microbiol (praha), Dec 2015
The aim of the study was to investigate anti-Outer membrane protein C (anti-OmpC) antibodies, aimed at porin C, which is embedded in the outer membrane of gram-negative bacteria, in patients with colorectal adenoma (CRA), CRC and controls.
Evaluation of use of risedronate as an antibiofilm agent.
New
Noronha et al., Mumbai, India. In J Med Microbiol, Nov 2015
UNASSIGNED: Escherichia coli cra null mutants have been reported in literature to be impaired in biofilm formation.
Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas.
New
Little et al., Ottawa, Canada. In Int J Epidemiol, Nov 2015
Most CRCs develop from colorectal adenomas (CRA).
Evaluation of Ica Gene in Comparison with Phenotypic Methods for Detection of Biofilm Production by Coagulase Negative Staphylococci in a Tertiary Care Hospital.
New
Divya et al., India. In J Clin Diagn Res, Aug 2015
MATERIALS AND METHODS: A total of 96 clinical isolates of CoNS were characterized and subjected to biofilm detection by tissue culture plate method (TCP), tube method (TM), congo red agar method (CRA) and PCR.
Advanced progress on the relationship between RA and its receptors and malignant tumors.
Review
Li et al., Dalian, China. In Crit Rev Oncol Hematol, 2014
Retinoic acid (RA) is an active derivative of vitamin A, and it has different isomers, including ATRA (all-trans-retinoic acid), 13-cRA (13-cis-retinoic acid) and 9-cRA (9-cis-retinoic acid), etc. Combining with RARs and RXRs, RA plays important roles not only in embryonic development but also in cellular growth and differentiation through transcriptional regulation of its target genes.
Consensus on the Prevention, Screening, Early Diagnosis and Treatment of Colorectal Tumors in China: Chinese Society of Gastroenterology, October 14-15, 2011, Shanghai, China.
Gao et al., Shanghai, China. In Gastrointest Tumors, 2014
Colorectal adenoma (CRA) is the most important precancerous disease of CRC.
Association between Helicobacter pylori infection and the risk of colorectal neoplasia: a systematic review and meta-analysis.
Review
Fan et al., Xi'an, China. In Colorectal Dis, 2013
RESULTS: Twenty-seven studies including 3792 cases of colorectal adenoma (CRA) and 3488 cases of colorectal cancer (CRC) were identified.
Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission.
Impact
Modak et al., New York City, United States. In J Clin Oncol, 2012
PATIENTS AND METHODS: One hundred sixty-nine children diagnosed with stage 4 NB (1988 to 2008) were enrolled onto consecutive anti-GD2 murine MoAb 3F8 ± GM-CSF ± 13-cis-retinoic acid (CRA) protocols after achieving first remission (complete remission/very good partial remission).
Clinical trials in chemoprevention of head and neck cancers.
Review
Wang et al., Boston, United States. In Rev Recent Clin Trials, 2012
Based on our review, the most extensively studied agents/compounds for chemoprevention continue to be retinoids (e.g., 13-cRA).
System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk.
Review
Chen et al., Xinxiang, China. In Tumour Biol, 2012
The relationships between some metabolic (including EPHX1, GSTs and NQO1) gene polymorphisms and colorectal adenoma (CRA) risk have been commonly studied, and no conclusions are available up to now.
Biofilm formation in Escherichia coli cra mutants is impaired due to down-regulation of curli biosynthesis.
GeneRIF
Noronha et al., Mumbai, India. In Arch Microbiol, 2011
Curli biosynthesis is regulated by Cra. Cra mutants are inpaired in iofilm formation.
Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.
GeneRIF
Dudley et al., Chicago, United States. In Circulation, 2011
RBM25/LUC7L3-mediated abnormal SCN5A mRNA splicing reduced Na+ channel current 91.1+/-9.3% to a range known to cause sudden death.
Novel members of the Cra regulon involved in carbon metabolism in Escherichia coli.
GeneRIF
Ishihama et al., Koganei, Japan. In J Bacteriol, 2011
Two lines of evidence indicate that a total of as many as 178 promoters are under the control of Cra.
Effect of cra gene knockout together with edd and iclR genes knockout on the metabolism in Escherichia coli.
GeneRIF
Shimizu et al., Iizuka, Japan. In Arch Microbiol, 2008
The glucose uptake rate and the acetate production rate were increased with less acetate consumption for the cra mutant.
The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human.
GeneRIF
Séraphin et al., Heidelberg, Germany. In Nucleic Acids Res, 2006
Luc7A is a new U1 snRNP-associated splicing factor.
Placebo-controlled trial of 13-cis-retinoic acid activity on retinoic acid receptor-beta expression in a population at high risk: implications for chemoprevention of lung cancer.
Impact
Bradley et al., Montréal, Canada. In J Clin Oncol, 1999
PURPOSE: To establish the incidence of abnormalities in the expression of retinoic acid receptor-beta (RARbeta) in bronchial cells and determine the capacity of 13-cis-retinoic acid (13-CRA) to correct such abnormalities.
Phase I clinical and pharmacologic study of 13-cis-retinoic acid, interferon alfa, and paclitaxel in patients with prostate cancer and other advanced malignancies.
Impact
Hait et al., New Brunswick, United States. In J Clin Oncol, 1999
A phase I trial of 13-cis-retinoic acid (CRA), IFNalpha, and paclitaxel (TAX) was conducted to determine the toxicity and recommended phase II dose of this combination.
Interferon alfa-2a and 13-cis-retinoic acid in renal cell carcinoma: antitumor activity in a phase II trial and interactions in vitro.
Impact
Nanus et al., New York City, United States. In J Clin Oncol, 1995
PURPOSE: A phase II trial of interferon alfa-2a (IFN) and 13-cis-retinoic acid (CRA) was conducted in patients with renal cell carcinoma (RCC).
Retinoids in cancer therapy.
Review
Impact
Friedman et al., Bethesda, United States. In J Clin Oncol, 1992
Additionally, the combination of 13-cis-retinoic acid (cRA) with interferon alpha (IFN alpha) has produced high objective response rates for patients with squamous cell carcinomas of the head and neck and of the cervix.
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