Integration of the Rac1- and actin-binding properties of Coronin-1C.
Bristol, United Kingdom. In Small Gtpases, 2014
We recently reported 2 interactions that were unique to coronin-1C: binding of a Rac1 inhibitor, RCC2, to the unique linker region and Rac1 itself to the propeller domain in a manner that differs from that proposed for other coronins.
CRN2 enhances the invasiveness of glioblastoma cells.
Hamburg, Germany. In Neuro Oncol, 2013
BACKGROUND: Movement of tumor cells involves dynamic remodeling of the actin cytoskeleton, which is regulated by actin binding proteins, such as CRN2 (synonyms: coronin 1C, coronin 3).
Rab27a, actin and beta-cell endocytosis.
Ōita, Japan. In Endocr J, 2010
Recently, we searched for Rab27a-interacting proteins and identified coronin 3. Unexpectedly, coronin 3 only bound GDP-Rab27a and this interaction regulated post-exocytotic stages via reorganization of the actin cytoskeleton.
The role of mammalian coronins in development and disease.
Chapel Hill, United States. In Subcell Biochem, 2007
This review primarily focuses on Coronin 1C (HGNC symbol: CORO1C, also known as Coronin 3) which is a transcriptionally dynamic gene that is up-regulated in multiple types of clinically aggressive cancer.
Coronin structure and implications.
Brisbane, Australia. In Subcell Biochem, 2007
There are indications that this modification regulates the quaternary structure of coronin 3 (1C) and thus has implications for the cellular localisation and the general link between signalling and cytoskeletal remodelling.