Cofactor-independent oxidases and oxygenases.
Münster, Germany. In Appl Microbiol Biotechnol, 2010
Among the cofactor-independent oxidases, urate oxidase, coproporphyrinogen oxidase, and formylglycine-generating enzyme are of mechanistic as well as medical interest.
Between a rock and a hard place: trace element nutrition in Chlamydomonas.
Los Angeles, United States. In Biochim Biophys Acta, 2006
Oxygen-dependent enzymes in the tetrapyrrole pathway (coproporphyrinogen oxidase and aerobic oxidative cyclase) are also increased in expression and activity by as much as 10-fold but the connection between copper nutrition and tetrapyrroles is not understood.
Terminal steps of haem biosynthesis.
Athens, United States. In Biochem Soc Trans, 2002
The terminal three steps in haem biosynthesis are the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, followed by the six-electron oxidation of protoporphyrinogen to protoporphyrin IX, and finally the insertion of ferrous iron to form haem. Interestingly, Nature has evolved distinct enzymic machinery to deal with the antepenultimate (coproporphyrinogen oxidase) and penultimate (protoporphyrinogen oxidase) steps for aerobic compared with anaerobic organisms.
Alcohol and porphyrin metabolism.
Marburg an der Lahn, Germany. In Alcohol Alcohol, 2000
Ethanol suppresses the activity of porphobilinogen synthase (synonym: delta-aminolevulinic acid dehydratase), uroporphyrinogen decarboxylase, coproporphyrinogen oxidase and ferrochelatase, whereas it induces the first and rate-limiting enzyme in the pathway, delta-aminolevulinic acid synthase and also porphobilinogen deaminase.
The primary enzyme defect in hereditary coproporphyria.
In Lancet, 1977
The activity of coproporphyrinogen oxidase (E.C. 220.127.116.11) in cultured skin fibroblasts from three patients with hereditary coproporphyria (H.C.) was approximately half that in fibroblasts from normal subjects and patients with other types of porphyria.