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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Complement factor H

Complement Factor H, factor H, CFH
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011] (from NCBI)
Papers using Complement Factor H antibodies
Papers on Complement Factor H
Factor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate.
GeneRIF
van den Born et al., Groningen, Netherlands. In J Biol Chem, 2012
Factor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate.
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.
GeneRIF
Zhang et al., Chengdu, China. In Proc Natl Acad Sci U S A, 2012
CFH influences age-related macular degeneration risk by modulating oxidative stress, inflammation, and abnormal angiogenesis
Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.
GeneRIF
Józsi et al., Jena, Germany. In J Immunol, 2012
we show that native factor H, factor H-like protein 1, and factor H-related protein 1 (CFHR1) bind to PTX3
Choroidal thickness, vascular hyperpermeability, and complement factor H in age-related macular degeneration and polypoidal choroidal vasculopathy.
GeneRIF
Yoshimura et al., Kyoto, Japan. In Invest Ophthalmol Vis Sci, 2012
Choroidal thickness is related to the AMD subtypes, choroidal hyperpermeability, and I62V CFH gene polymorphism.
The critical role of adrenomedullin and its binding protein, AMBP-1, in neuroprotection.
GeneRIF
Wang et al., North Bay Shore, United States. In Biol Chem, 2012
role of adrenomedullin and its binding protein, AMBP-1, in neuroprotection
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