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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Complement component 5a receptor 1

C5a, Complement C5, C5aR
likely component of the classical pathway of the complement cascade; may be involved with tissue injury associated with ischemia or sepsis; may be a component of the membrane attack complex [RGD, Feb 2006] (from NCBI)
Papers using C5a antibodies
Imagable 4T1 model for the study of late stage breast cancer
Yoon Park Jung Han et al., In Breast Cancer Research : BCR, 2007
... myeloid cells (TREM)-1 from R and D Systems (Minneapolis, MN, USA); ELISA kits for complement fragment 5a (C5a) and interleukin (IL)-16 from USCN Life Science and Technology Company (Missouri ...
Papers on C5a
Roles of promoter and 3' untranslated motifs in expression of the human C5a receptor.
van den Berg et al., Cardiff, United Kingdom. In Mol Immunol, 2012
Analysis of the 3'UTR of the C5aR mRNA showed that it contained two AU-rich elements (AREs), however site directed mutagenesis showed that these had no effect on basal expression.
Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway.
Stadnyk et al., Halifax, Canada. In Am J Physiol Cell Physiol, 2012
Intestinal epithelial cells express C5aR apically and directly respond to C5a through the ERK signaling pathway.
Complement C5A regulates prolabor mediators in human placenta.
Permezel et al., Melbourne, Australia. In Biol Reprod, 2012
Complement C5a upregulates prolabor mediators in human gestational tissues via CD88-mediated NFKB activation.
Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.
Ward et al., Ann Arbor, United States. In J Immunol, 2012
C5a robustly suppresses IL-27(p28) gene expression and release in peritoneal macrophages.
C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity.
Song et al., Philadelphia, United States. In J Immunol, 2012
a surprising role for the 3'-untranslated region of C5aR mRNA in regulating C5aR protein targeting to the plasma membrane.
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