COMMD1/Murr1 reinforces HIV-1 latent infection through IκB-α stabilization.
Kumamoto, Japan. In J Virol, Mar 2015
Here we show that the expression of IκB-α, an endogenous inhibitor of NF-κB, is enhanced by latent HIV-1 infection via induction of the host-derived factor COMMD1/Murr1 in myeloid cells but not in lymphoid cells by using four sets of latently HIV-1-infected cells and the respective parental cells.
Genomic Landscape of Primary Mediastinal B-Cell Lymphoma Cell Lines.
Braunschweig, Germany. In Plos One, 2014
2p15 (REL/COMMD1), 9p24 (JAK2, CD274), 16p13 (SOCS1, LITAF, CIITA); plus new or tenuously associated loci: 2p16 (MSH6), 6q23 (TNFAIP3), 9p22 (CDKN2A/B), 20p12 (PTPN1).
COMMD proteins: COMMing to the scene.
Ann Arbor, United States. In Cell Mol Life Sci, 2007
COMM Domain-containing or COMMD proteins are a recently discovered group of factors defined by the presence of a unique motif in their extreme carboxy termini (Copper metabolism MURR1, or COMM domain).