Lukomski et al., Morgantown, United States. In J Biol Chem, 2009
Group A Streptococcus (GAS) employs molecular mimicry by direct interactions between the cell surface streptococcal collagen-like protein-1 (Scl1) and the human collagen receptor, integrin alpha2beta1.
Groop et al., Malmö, Sweden. In J Clin Endocrinol Metab, 2002
To examine whether altered gene expression of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc is an inherited trait and is associated with muscle insulin resistance or type 2 diabetes, we measured mRNA levels of these genes by a relative quantitative RT-PCR method in muscle biopsies taken before and after an insulin clamp from 12 monozygotic twin pairs discordant for type 2 diabetes and 12 control subjects.
The collagen-like-protein (CLP) in sera of patients with scleroderma (n = 20) and controls with (n = 25) this disease as well as in scleroderma-patients under treatment with D-penicillamine (DPA) was determined.