Discovery of signature genes in gastric cancer associated with prognosis.
In Neoplasma, Feb 2016
A total of 17 genes were identified as signature genes, such as DAB2, ALDH2, CD58, CITED2, BNIP3L, SLC43A2, FAU and COL5A1.Many signature genes associated with prognosis of GC were identified in present study, some of which have been implicated in the pathogenesis of GC.
Systematically identify key genes in inflammatory and non-inflammatory breast cancer.
Chongqing, China. In Gene, Feb 2016
Here, we comprehensively analyzed and compared the transcriptional profiles from IBC and non-IBC patients using hierarchical clustering, protein-protein interaction (PPI) network, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) database analyses, and identified PDGFRβ, SUMO1, COL1A1, FYN, CAV1, COL5A1 and MMP2 to be the key genes for breast cancer.
Expression of genes involved in cellular adhesion and ECM-remodelling correlates with poor survival of renal cancer patients.
Warsaw, Poland. In J Urol, Dec 2015
The 10-gene expression signature (COL1A1, COL5A1, COL11A1, FN1, ICAM1, ITGAL, ITGAM, ITGB2, THBS2, and TIMP1) correlated with poor survival (HR=2.85,
The COL5A1 genotype is associated with range of motion.
Pusan, South Korea. In J Exerc Nutrition Biochem, Jun 2015
PURPOSE: The aim of our study was to investigate the association between COL5A1 genotype and Range of Motion as measured by the passive straight leg raise (SLR) and whole body join laxity (WBJL) in Asian population.
Osteoarthritis year in review 2014: genetics and genomics.
Lárisa, Greece. In Osteoarthritis Cartilage, 2014
In OA synovium elevation of collagens and cross-linking enzymes (COL1A1, COL5A1, PLOD2, LOX and TIMP1) responsive to TGF-β was found as well as differential expression pattern between different areas of the osteoarthritic synovial membrane.