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Cytidine monophosphate N-acetylneuraminic acid synthetase
CMP-N-acetylneuraminic acid synthetase, cytidine monophosphate N-acetylneuraminic acid synthetase
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Top mentioned proteins:
ACID, Neuraminidase, HAD, sialyltransferase, CAN
Papers on
CMP-N-acetylneuraminic acid synthetase
Immunoproteomic analysis of the protective response obtained with subunit and commercial vaccines against Glässer's disease in pigs.
León, Spain. In Vet Immunol Immunopathol, 2013
Among them, six proteins (FKBP-type peptidyl-prolyl cis-trans isomerase, neuraminidase exo-α-sialidase, xanthine-guanine phosphoribosyl transferase, CMP-N-acetylneuraminic acid synthetase, phenylalanyl-tRNA synthetase and glyceraldehyde 3-phosphate dehydrogenase) were found to be novel immunogens in H. parasuis.
A CMP-N-acetylneuraminic acid synthetase purified from a marine bacterium, Photobacterium leiognathi JT-SHIZ-145.
Iwata, Japan. In Biosci Biotechnol Biochem, 2010
A cytidine 5'-monophospho-N-acetylneuraminic acid (CMP-Neu5Ac) synthetase was found in a crude extract prepared from Photobacterium leiognathi JT-SHIZ-145, a marine bacterium that also produces a β-galactoside α2,6-sialyltransferase.
Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis.
Vienna, Austria. In Plant Physiol, 2008
In this study, we have generated transgenic Arabidopsis (Arabidopsis thaliana) plants expressing three key enzymes of the mammalian Neu5Ac biosynthesis pathway: UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, N-acetylneuraminic acid phosphate synthase, and CMP-N-acetylneuraminic acid synthetase.
Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell.
Suita, Japan. In Biochem Biophys Res Commun, 2006
In this study, we introduced two critical genes encoding human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter into tobacco suspension-cultured cell to pave a route for sialic biosynthetic pathway.
Nontypeable Haemophilus influenzae strain 2019 produces a biofilm containing N-acetylneuraminic acid that may mimic sialylated O-linked glycans.
Iowa City, United States. In Infect Immun, 2004
NTHI strain 2019 with mutations in the genes encoding CMP-N-acetylneuraminic acid synthetase (siaB), one of the three NTHI sialyltransferases (siaA), and the undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase homolog (wecA) produced significantly smaller amounts of biofilm.
CMP-N-acetylneuraminic acid synthetase from Escherichia coli K1 is a bifunctional enzyme: identification of minimal catalytic domain for synthetase activity and novel functional domain for platelet-activating factor acetylhydrolase activity.
Beijing, China. In J Biol Chem, 2004
Escherichia coli CMP-NeuAc synthetase (EC 2.7.7.43) catalyzes the synthesis of CMP-NeuAc from CTP and NeuAc, which is essential for the formation of capsule polysialylate for strain K1.
Purification of CMP-N-acetylneuraminic acid synthetase from bovine anterior pituitary glands.
Bethesda, United States. In Glycobiology, 1999
CMP-neuNAc synthetase catalyzes the formation of this substrate, CMP-neuNAc, from CTP and neuNAc.
Characterization of cpsF and its product CMP-N-acetylneuraminic acid synthetase, a group B streptococcal enzyme that can function in K1 capsular polysaccharide biosynthesis in Escherichia coli.
Boston, United States. In Mol Microbiol, 1996
Group B Streptococcus (GBS) is the foremost cause of neonatal sepsis and meningitis in the United States.
Identification and characterization of genes required for post-translational modification of Campylobacter coli VC167 flagellin.
Bethesda, United States. In Mol Microbiol, 1996
The ptmB gene encodes a protein of predicted M(r) 26,598 with significant homology to CMP-N-acetylneuraminic acid synthetase enzymes involved in sialic acid capsular biosynthesis in Neisseria meninigitidis and Escherichia coli K1.
Lec32 is a new mutation in Chinese hamster ovary cells that essentially abrogates CMP-N-acetylneuraminic acid synthetase activity.
New York City, United States. In J Biol Chem, 1996
LEC29.Lec32 is a glycosylation mutant that was isolated from a selection of mutagenized Chinese hamster ovary (CHO) cells for lectin resistance.
Characterization of CMP-N-acetylneuraminic acid synthetase of group B streptococci.
Boston, United States. In J Bacteriol, 1994
The capsular polysaccharide is a critical virulence factor for group B streptococci associated with human infections, yet little is known about capsule biosynthesis.
Sialic acid metabolism in rat liver: effect of carbon tetrachloride.
In Life Sci, 1983
Moderate increases in the specific activities of CMP-N-acetylneuraminic acid synthetase and sialyltransferase were also observed.
Synthesis of N-acetylneuraminic acid and of CMP-N-acetylneuraminic acid in the rat liver cell.
In Biochem J, 1983
It is suggested that the cytosolic enzyme N-acetylneuraminic acid 9-phosphate phosphatase is working in concert with the nuclear localized enzyme CMP-N-acetylneuraminic acid synthetase.
Sialic acid metabolism in regenerating rat liver.
In Cancer Lett, 1981
High levels of CMP-N-acetylneuraminic acid synthetase and sialyltransferase were observed both in regenerating liver as well as in the liver of sham-operated rats.
Effects of essential fatty acid deficiency during late gestation on brain N-acetylneuraminic acid metabolism and behaviour in the progeny.
In Br J Nutr, 1981
and cytidine monophosphate N-acetylneuraminic acid synthetase (CMP-NeuNAc synthetase) activities were measured at days, 7, 14, 21 and 168 in the progeny.
