gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Exosome component 5

CML28, hRrp46p, p12b
Top mentioned proteins: CAN, ACID, GST, MHC, Phosphogluconate Dehydrogenase
Papers on CML28
Prediction and identification of HLA-A*0201-restricted epitopes from leukemia-associated protein MLAA-22 which elicit cytotoxic T lymphocytes.
Zhang et al., Xi'an, China. In Med Oncol, 2014
The percentage of positive T2 cells treated with MLAA-22(379-387) was about 96.3%, which is even higher than that of the positive control peptide CML28(173-181) (95.1%).
Interaction of human genes WT1 and CML28 in leukemic cells.
Zhang et al., Wuhan, China. In J Huazhong Univ Sci Technolog Med Sci, 2013
Earlier studies have shown both Wilms' tumor 1 suppressor gene (WT1) and CML28 abnormally expressed in malignant diseases of the hematopoietic system and WT1 played an important role in leukemogenesis.
[Expression and purification of GST-CML28 fusion protein and preparation of its polyclonal antibody].
Zhang et al., Wuhan, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2012
This study was aimed to investigate the expression of GST-CML28 in Escherichia Coli and to prepare its antibody.
Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation.
Yuan et al., Taipei, Taiwan. In Rna, 2010
Results suggest that Rrp46 forms a homodimer separately from exosome complexes and, depending on species, is a structural component of the machinery that cleaves DNA during apoptosis.
[In vitro cytotoxic effects of CML28 specific T cells on acute leukemia cells].
Huang et al., Wuhan, China. In Zhonghua Xue Ye Xue Za Zhi, 2009
METHODS: aAPCs were developed by coating a human leukocyte antigen-immunoglobulin fusion protein ( HLA-lg), which was connected each one of the four CML28 antigen epitopes (DLMSSTKGL, DLMSSTKGL, ALFCGVACA, VLTFALDSV), and CD28-specific antibody, to magnet-beads CML cell specific peptides (CML28) served as target peptides.
Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene.
Xie et al., Hong Kong, Hong Kong. In Cancer Immunol Immunother, 2008
rAAV/CML28-transduced DCs vaccine may serve as a feasible approach for the treatment of CML28-associated cancers.
[Activation of specific T lymphocyte induced by artificial antigen presenting cell complex in vitro].
Huang et al., Wuhan, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2008
The specific antigen of chronic myeloid leukemia CML-28 was screened as objective antigen peptide by using magnetic microbeads as vector; the CML-28 epitope sequence (Vltfaldsv) was obtained by antigen epitope prediction software; this epitope was coupled with MHC molecule and used as first signal molecule, the B7-1 molecule was used as second signal molecule; these 2 molecules simultaneously were loaded onto surface of magnetic microbeads so as to contract aAPC complex.
Selection of HLA-A2 restricted CML28 peptide by artificial antigen-presenting cells.
Huang et al., China. In J Immunother, 2008
We adopted the SYFPEITHI database to predict human leukocyte antigen-A2 restricted CML28 peptide.
The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA.
Gao et al., Beijing, China. In Proc Natl Acad Sci U S A, 2007
In vitro pull-down assays indicated that ZAP directly interacted with the exosome component hRrp46p and that the binding region of ZAP was mapped to amino acids 224-254.
Identification of a new HLA-A*0201-restricted cytotoxic T lymphocyte epitope from CML28.
Wu et al., Chongqing, China. In Cancer Immunol Immunother, 2006
CML28, a recently discovered cancer-testis (CT) antigen from chronic myelogenous leukemia, is considered to be a promising target of tumor-specific immunotherapy.
Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector.
Huang et al., Wuhan, China. In Biochem Biophys Res Commun, 2006
These results in our study indicates gene silencing of SOCS1 remarkably enhanced the cytotoxicity efficiency of CML28 DNA vaccine in DCs.
[Monitoring CML28 mRNA levels in patients before and after HSCT by real-time quantitative RT-PCR].
Cao et al., Wuhan, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2005
The purpose of this study was to establish a SYBR Green I real-time quantitative RT-PCR method for investigating the correlation between CML28 mRNA expression levels and relapse of leukemia after allo-hematopoietic stem cell transplantation (HSCT).
Construction and expression of dendritic cell nucleic acid vaccine containing CML28 gene in human dendritic cells.
Tan et al., China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2005
This study was aimed to construct nucleic acid vaccine containing the coding region of the CML28 gene and to express it in human dendritic cells.
Graft-versus-leukemia target antigens in chronic myelogenous leukemia are expressed on myeloid progenitor cells.
Ritz et al., Boston, United States. In Clin Cancer Res, 2005
We previously reported the identification of a high titer-specific immunoglobulin G response against two novel leukemia-associated antigens, CML28 and CML66, which correlated with immune-induced remission.
The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus.
Pruijn et al., Nijmegen, Netherlands. In J Biol Chem, 2003
This interaction is most likely mediated by protein-protein interactions with two other exosome subunits, hRrp46p and hRrp41p, one of which was confirmed in a mammalian two-hybrid system.
Novel targeted and immunotherapeutic strategies in chronic myeloid leukemia.
Scheinberg et al., New York City, United States. In Semin Hematol, 2003
Antigens under investigation include bcr-abl, PR1, Wilms tumor protein (WT1), minor histocompatibility antigens (mH), CML-66, CML-28, and survivin.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Pruijn et al., Nijmegen, Netherlands. In J Mol Biol, 2002
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Protein-protein interactions of hCsl4p with other human exosome subunits.
Pruijn et al., Nijmegen, Netherlands. In J Mol Biol, 2002
association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p and hRrp46p
share on facebooktweetadd +1mail to friends