Altered activation of the diaphragm in late-onset Pompe disease.
Gainesville, United States. In Respir Physiol Neurobiol, Mar 2016
We studied the activation of the diaphragm using bilateral phrenic magnetic stimulation and hypothesized that diaphragm compound muscle action potential (CMAP) amplitude and evoked transdiaphragmatic pressure (Twitch PDI) would correlate to disease severity.
Force-Field Induced Bias in the Structure of Aβ21-30: A Comparison of OPLS, AMBER, CHARMM, and GROMOS Force Fields.
Philadelphia, United States. In J Chem Inf Model, Jan 2016
In this work we examine the dynamics of an intrinsically disordered protein fragment of the amyloid β, the Aβ21-30, under seven commonly used molecular dynamics force fields (OPLS-AA, CHARMM27-CMAP, AMBER99, AMBER99SB, AMBER99SB-ILDN, AMBER03, and GROMOS53A6), and three water models (TIP3P, TIP4P, and SPC/E).
Auxin regulation of cell polarity in plants.
Fuzhou, China. In Curr Opin Plant Biol, Dec 2015
These findings beg for the question about the nature of auxin receptors that regulate these responses and renew the interest in ABP1 as a cell surface auxin receptor, including the work showing auxin-binding protein 1 (ABP1) interacts with the extracellular domain of the transmembrane kinase (TMK) receptor-like kinases in an auxin-dependent manner, as well as the debate on this auxin binding protein discovered about 40 years ago.
Revisiting Apoplastic Auxin Signaling Mediated by AUXIN BINDING PROTEIN 1.
Chinju, South Korea. In Mol Cells, Dec 2015
It has been suggested that AUXIN BINDING PROTEIN 1 (ABP1) functions as an apoplastic auxin receptor, and is known to be involved in the post-transcriptional process, and largely independent of the already well-known SKP-cullin-F-box-transport inhibitor response (TIR1) /auxin signaling F-box (AFB) (SCF(TIR1/AFB)) pathway.
Auxin transporters and binding proteins at a glance.
Gent, Belgium. In J Cell Sci, 2015
SCF(TIR1) [a SKP1-cullin-1-F-box complex that contains transport inhibitor response 1 (TIR1) as the F-box protein] and S-phase-kinase-associated protein 2 (SKP2) localize to the nucleus, whereas auxin-binding protein 1 (ABP1), predominantly associates with the endoplasmic reticulum and cell surface.