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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Calmodulin-like 5

CLSP, CAR-like soluble protein, calmodulin-like protein 5
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, Lysozyme, V1a, HAD, SET
Papers on CLSP
Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.
Matsuoka, Tokyo, Japan. In Mol Neurobiol, Jun 2015
Calmodulin-like skin protein (CLSP) has recently been identified as a physiological agonist of htHNR with 10(5)-fold more potent anti-cell death activity than Humanin.
Secreted calmodulin-like skin protein ameliorates scopolamine-induced memory impairment.
Matsuoka et al., Iwaki, Japan. In Neuroreport, 2014
Recently, calmodulin-like skin protein (CLSP) has been shown to be secreted from skin tissues, contain a region minimally similar to the core region of Humanin, and inhibit AD-related neuronal death through the heterotrimeric Humanin receptor on the cell surface in vitro.
Protein biomarkers in vernix with potential to predict the development of atopic eczema in early childhood.
Scheynius et al., Stockholm, Sweden. In Allergy, 2014
Polyubiquitin-C and calmodulin-like protein 5 showed strong negative correlation to the AE group, with a correlation coefficient of 0.73 and 0.68, respectively, and a P-value of 8.2 E-7 and 1.8 E-5, respectively.
Specific expression of k63-linked ubiquitination of calmodulin-like protein 5 in breast cancer of premenopausal patients.
Walgenbach-Brünagel et al., Bonn, Germany. In J Cancer Res Clin Oncol, 2013
Based on previous findings, the aim of this study was to evaluate the ubiquitination of CALML5 in breast cancer patients.
Molecular characteristic and expression analysis of collagenolytic serine protease from the Chinese mitten crab Eriocheir sinensis with defense response to Vibrio anguillarum challenge.
Zhang et al., Xinxiang, China. In Genet Mol Res, 2013
A novel collagenolytic serine protease (CLSP) was cloned from the hemocytes of the Chinese mitten crab Eriocheir sinensis (Es-CLSP).
Calmodulin-like skin protein level increases in the differentiated epidermal layers in atopic dermatitis.
de Lacharriere et al., Aulnay-sous-Bois, France. In Exp Dermatol, 2013
The calmodulin-like skin protein (CLSP), which is expressed in the differentiated epidermis, is believed to modulate the function of calcium-dependent proteins involved in barrier formation and is significantly increased in the epidermis of psoriatic patients.
Loss of ELF3 immunoexpression is useful for detecting oral squamous cell carcinoma but not for distinguishing between grades of epithelial dysplasia.
Farah et al., Australia. In Ann Diagn Pathol, 2013
Published microarray data has denoted dysregulation of CLSP, ELF3, IFI44, USP18, and CXCL13 genes in potentially malignant oral disorders.
Molecular cloning and expression analysis of chymotrypsin-like serine protease from the redclaw crayfish (Cherax quadricarinatus): a possible role in the junior and adult innate immune systems.
Shi et al., Wuxi, China. In Fish Shellfish Immunol, 2013
A novel chymotrypsin-like serine protease (CLSP) was isolated from the hepatopancreas of the redclaw crayfish Cherax quadricarinatus (Cq-chy).
Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptor.
Matsuoka et al., Tokyo, Japan. In Cell Death Dis, 2012
In the current study, calmodulin-like skin protein (CLSP), a calmodulin relative with an undefined function, was shown to be secreted and inhibit neuronal death via the htHNR with an EC50 of 10-100 pM.
Identification of specific nuclear structural protein alterations in human breast cancer.
Walgenbach-Brünagel et al., Bonn, Germany. In J Cell Biochem, 2011
Two of the breast cancer-specific proteins have been confirmed to be calponin h2 and calmodulin-like protein 5 by one-dimensional immunoblot.
[Comparison of 2,3-butanediol production by several strains and optimization of the fermentation medium].
Liu et al., Beijing, China. In Sheng Wu Gong Cheng Xue Bao, 2011
The optimum compositions were as follows: glucose 90 g/L, (NH4)2HPO4 3 g/L, CLSP 6 g/L, sodium acetate 5 g/L, KCl 0.4 g/L, MgSO4 0.1 g/L, FeSO4 x 7H2O 0.02 g/L, MnSO4 0.01 g/L.
Positive and negative regulation of adenovirus infection by CAR-like soluble protein, CLSP.
Mizuguchi et al., Ōsaka, Japan. In Gene Ther, 2007
These results suggest that CLSP may play a role in the antiviral defense of the host in rodent animals.
[Role of a novel protein, CAR-like soluble protein (CLSP), in adenovirus infection].
Kawabata, Ōsaka, Japan. In Yakugaku Zasshi, 2007
Recently, we have identified a novel protein, CAR-like soluble protein (CLSP), which is closely related to CAR.
Influence of calcium on the proteolytic degradation of the calmodulin-like skin protein (calmodulin-like protein 5) in psoriatic epidermis.
Schmidt et al., France. In Exp Dermatol, 2006
abnormal elevated levels of CLSP, characteristic of psoriatic epidermis, were probably not due to an overexpression of the protein, but most likely the result of its non-degradation
A structural and dynamic characterization of the EF-hand protein CLSP.
Luchinat et al., Sesto Fiorentino, Italy. In Structure, 2006
The structure and dynamics of human calmodulin-like skin protein (CLSP) have been characterized by NMR spectroscopy.
The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis.
Pettersson et al., Stockholm, Sweden. In Exp Cell Res, 2006
The coxsackie- and adenovirus receptor is localized to epithelial tight junctions in vivo where it may play a role in the regulation of epithelial permeability and tissue homeostasis.
Gene design of signal sequence for the effective secretion of recombinant protein using insect cell.
Yoshida et al., Kodaira, Japan. In Nucleic Acids Symp Ser (oxf), 2004
In order to increase the proteinic secretion quantity of production in insect cell, the chicken lysozyme signal peptide (CLSP) was altered, and the effect of mutations on secretion of human lysozyme (HLY), the bovine interferon beta-3, and the equine interferon alpha-1 were studied.
Structural requirements of signal peptide in insect cell.
Yoshida et al., Kodaira, Japan. In Nucleic Acids Symp Ser (oxf), 2003
In order to increase the proteinic secretion quantity of production in insect cell, the N-terminal and the hydrophobic core region of the chicken lysozyme signal peptide (CLSP) was altered.
Cation- and peptide-binding properties of human calmodulin-like skin protein.
Cox et al., Genève, Switzerland. In Biochemistry, 2002
An investigation of the cation-binding properties of CLSP and the ensuing conformational changes finds that, with its high- and low-affinity Ca+2+-binding sites and a pronounced effect of Mg2+, CLSP is more similar to troponin C than to calmodulin.
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