Wasted and weak arm in a young man.
Kenya. In J Neurol Neurosurg Psychiatry, 30 Nov 2013
BACKGROUND: There are many causes of progressive muscle wasting and weakness from which motor neuron disease (MND) is a common and dreaded differential diagnosis.
Characterization of Neuronal Ceroid-Lipofuscinosis in 3 Cats.
Saint Paul, United States. In Vet Pathol, 11 Oct 2013
Molecular genetic characterization in the 1 cat from which DNA was available did not reveal any plausible disease-causing mutations of the CLN1 (PPT1), CLN3, CLN5, CLN8, and CLN10 (CTSD) genes.
Neuropathy target esterase (NTE): overview and future.
Ann Arbor, United States. In Chem Biol Interact, Apr 2013
Mutations in the catalytic domain of NTE (PNPLA6) are associated with a slowly developing disease akin to OP neuropathy and hereditary spastic paraplegia called NTE-related motor neuron disorder (NTE-MND).
RNA dysregulation in diseases of motor neurons.
Philadelphia, United States. In Annu Rev Pathol, 2011
In children, inherited spinal muscular atrophies are the predominant diseases that affect motor neurons, whereas in adults, amyotrophic lateral sclerosis, which is inherited but mostly sporadic, is the most common MND.