Receptor Dissociation and B-Cell Activation.
Freiburg, Germany. In Curr Top Microbiol Immunol, Dec 2015
Although dominant for a long time, the cross-link model (CLM) of BCR activation is not supported by recent studies of the nanoscale organization of the BCR on the surface of resting B cells.
Impact of somatic mutations on patterns of metastasis in colorectal cancer.
New York City, United States. In J Gastrointest Oncol, Dec 2015
In patients who undergo resection of colorectal liver metastases (CLM) with curative intent, KRAS mutation is associated increased risk of recurrence, worse survival, and increased recurrence outside of the liver, particularly in the lung, but also in the brain and bone.