Alterations in Caenorhabditis elegans and Cronobacter sakazakii lipopolysaccharide during interaction.
Kāraikkudi, India. In Arch Microbiol, Mar 2015
atf-7, scl-2, cpr-2) and aging-related genes (skn-1, clk-2, bra-2, age-1, bec-1, daf-16, daf-2).
Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases.
Philadelphia, United States. In Sci Signal, 2014
These five complexes consist of tyrosine residues in the N-terminal juxtamembrane regions of colony-stimulating factor 1 receptor (CSF1R, Tyr(561)) and ephrin receptor A2 (EPHA2, Tyr(594)), tyrosine residues in the activation loops of the SRC kinase family member LCK (Tyr(394)) and insulin-like growth factor 1 receptor (IGF1R, Tyr(1166)), and a serine in a nuclear localization signal region of CDC-like kinase 2 (CLK2, Ser(142)).
IR laser-induced protein crystal transformation.
Martinsried, Germany. In Acta Crystallogr D Biol Crystallogr, 2014
Heating proved superior to traditional controlled dehydration by humidity change for the test cases CODH (carbon monoxide dehydrogenase) and CLK2 (a protein kinase).
Tel2: a common partner of PIK-related kinases and a link between DNA checkpoint and nutritional response?
Kyoto, Japan. In Genes Cells, 2007
A recent paper (Hayashi et al. 2007) in this issue of Genes to Cells shows that the fission yeast Schizosaccharomyces pombe Tel2, a homologue of mammalian/worm CLK2/Clk-2/Rad-5, physically interacts with all the phosphoinositide 3-kinase-related kinases (PIKKs) that include Rad3/Tel1 (ATR/ATM homologues), Tor1/Tor2 (TOR kinases) and Tra1/Tra2 (TRRAP homologues), raising the possibility that Tel2 family proteins link various PIKK-related cellular processes by interacting with PIKK family proteins.