Targeting platelet receptor function in thrombus formation: the risk of bleeding.
Maastricht, Netherlands. In Blood Rev, 2014
Discussed are receptors for thrombin, thromboxane, ADP, ATP, prostaglandins, von Willebrand factor, collagen, CLEC-2 ligand, fibrinogen and laminin.
Platelets in lymph vessel development and integrity.
Birmingham, United Kingdom. In Adv Anat Embryol Cell Biol, 2013
The platelet C-type lectin receptor CLEC-2 and its ligand, the transmembrane protein Podoplanin, which is expressed at high levels on lymphatic endothelial cells (LECs), are required to prevent mixing of the blood and lymphatic vasculatures during mid-gestation.