gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cold inducible RNA binding protein

CIRP, cold-inducible RNA-binding protein
expression decreased by ischemia and H2O2; may mediate generation of reactive oxygen species [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, RBM3, V1a, ACID, HAD
Papers on CIRP
A deficiency in cold-inducible RNA-binding protein accelerates the inflammation phase and improves wound healing.
Wang et al., North Bay Shore, United States. In Int J Mol Med, Feb 2016
Cold-inducible RNA-binding protein (CIRP) belongs to a family of cold-shock proteins that are expressed in high levels under stress conditions.
Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.
Songyang et al., Guangzhou, China. In Nucleic Acids Res, Jan 2016
To better understand telomerase regulation, we performed immunoprecipitations coupled with mass spectrometry (IP-MS) and identified cold inducible RNA-binding protein (CIRP or hnRNP A18) as a telomerase-interacting factor.
Developmental competence of mature yak vitrified-warmed oocytes is enhanced by IGF-I via modulation of CIRP during in vitro maturation.
Yu et al., Lanzhou, China. In Cryobiology, Dec 2015
The objective of this study was to investigate whether developmental competence of mature vitrified-warmed yak (Bos grunniens) oocytes can be enhanced by supplemented insulin-like growth factor I (IGF-1) during in vitro maturation (IVM), and its relationship with the expression of cold-inducible RNA-binding protein (CIRP).
Comparison of thyroid hormone-dependent gene responses in vivo and in organ culture of the American bullfrog (Rana (Lithobates) catesbeiana) lung.
Helbing et al., Victoria, Canada. In Comp Biochem Physiol Part D Genomics Proteomics, Dec 2015
In contrast, mRNA representing Krüppel-like factor 9 and cold-inducible RNA binding protein revealed differential effects between natural and precocious metamorphosis.
Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis.
Xu et al., Beijing, China. In Brain Res, Nov 2015
Cold-inducible RNA-binding protein (CIRP) is induced by mild hypothermia in several mammals, but the precise mechanism by which CIRP mediates hypothermia-induced neuroprotection remains unknown.
The systemic control of circadian gene expression.
Schibler et al., Genève, Switzerland. In Diabetes Obes Metab, Sep 2015
The latter include signals depending on feeding cycles, glucocorticoid hormones, rhythmic blood-borne signals eliciting daily changes in actin dynamics and serum response factor (SRF) activity, and sensors of body temperature rhythms, such as heat shock transcription factors and the cold-inducible RNA-binding protein CIRP.
Cold-inducible RNA-binding protein, CIRP, inhibits DNA damage-induced apoptosis by regulating p53.
Jang et al., Inch'ŏn, South Korea. In Biochem Biophys Res Commun, Sep 2015
CIRP has been implicated in apoptosis, yet its mechanism of action remains unknown.
[Cold inducible RNA-binding protein inhibits hippocampal neuronal apoptosis under hypothermia by regulating redox system].
Li et al., Daqing, China. In Sheng Li Xue Bao, Sep 2015
In this study, we intend to confirm our hypothesis that cold inducible RNA-binding protein (CIRP) can inhibit neuronal apoptosis through suppressing the formation of oxygen free radicals under hypothermia.
The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome.
Li et al., Changsha, China. In Plos One, 2014
Cold-inducible RNA-binding protein (CIRP) is a widely distributed cold-shock protein that plays a proinflammatory role in sepsis and that may induce organ damage.
Effects of Mild Chronic Intermittent Cold Exposure on Rat Organs.
Luo et al., Xi'an, China. In Int J Biol Sci, 2014
In addition, we determined the expression levels of cold-inducible RNA binding protein (Cirbp) and thioredoxin (TRX) in rat tissues after 2 weeks of CIC exposure.
Effects of sleep and wake on astrocytes: clues from molecular and ultrastructural studies.
Cirelli et al., Madison, United States. In Bmc Biol, 2014
Sleep upregulates a few select genes, like Cirp and Uba1, whereas wake upregulates many genes related to metabolism, the extracellular matrix and cytoskeleton, including Trio, Synj2 and Gem, which are involved in the elongation of peripheral astrocytic processes.
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.
Wang et al., New York City, United States. In Nat Med, 2013
Here we report increased levels of cold-inducible RNA-binding protein (CIRP) in the blood of individuals admitted to the surgical intensive care unit with hemorrhagic shock.
Cold-inducible RNA-binding protein modulates circadian gene expression posttranscriptionally.
Schibler et al., Genève, Switzerland. In Science, 2012
CIRP confers robustness to circadian oscillators through regulation of CLOCK expression.
Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.
Fujita et al., Kyoto, Japan. In Proc Natl Acad Sci U S A, 2012
Cirp functions to fine-tune the proliferation of undifferentiated spermatogonia by interacting with Dyrk1b.
Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain.
Xue et al., Beijing, China. In Brain Res, 2010
The analysis did not reveal any correlation between the three metabolic parameters and CIRP mRNA expression induced by hypothermia.
A new generation of proto-oncogenes: cold-inducible RNA binding proteins.
Lleonart, Barcelona, Spain. In Biochim Biophys Acta, 2010
This review focuses on the roles of two major cold-inducible RNA binding proteins known in human cells: CIRP and RBM3.
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity.
Getzenberg et al., Baltimore, United States. In J Cell Biochem, 2009
pharmacological modulation of RBM3 and CIRBP may represent novel therapeutic approaches for prostate cancer.
Overexpression of CIRP may reduce testicular damage induced by cryptorchidism.
Chen et al., Wuhan, China. In Clin Invest Med, 2008
Overexpression of CIRP may reduce testicular damage induced by cryptorchidism by down-regulating the levels of p53 and Fas.
Cold shock response in mammalian cells.
Fujita, Kyoto, Japan. In J Mol Microbiol Biotechnol, 1999
Furthermore, 32 degrees C induces expression of CIRP (cold-inducible RNA-binding protein), the first cold shock protein identified in mammalian cells, without recovery at 37 degrees C. Remniscent of HSP, CIRP is also expressed at 37 degrees C and developmentary regulated, possibly working as an RNA chaperone.
share on facebooktweetadd +1mail to friends