gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cyclin-dependent kinase 2 interacting protein

The protein encoded by this gene interacts with CDK2, MCM5, and CDC7, and is associated with the origin recognition complex protein ORC2. It acts as a homodimer and is involved in replication and ATR-mediated checkpoint signaling. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] (from NCBI)
Top mentioned proteins: PCNA, POLYMERASE, CDK2, HAD, NB1
Papers on CINP
Proceedings of the 2013 CINP summit: innovative partnerships to accelerate CNS drug discovery for improved patient care.
Race et al., Montréal, Canada. In Int J Neuropsychopharmacol, Feb 2015
In response to this state of affairs, the Collegium Internationale Neuro-Psychopharmacologicum (CINP) convened a summit to discuss ways to reverse this disturbing trend through new partnerships to accelerate CNS drug discovery.
Gene expression profiling on pre- and post-erlotinib tumors from patients with head and neck squamous cell carcinoma.
Delord et al., Toulouse, France. In Head Neck, 2013
Finally, the search of pharmacodynamic markers identified cyclin-dependent kinase 2-interacting protein (CINP) as a potential marker of erlotinib efficacy because its expression decreased only in patients who were responders to the treatment.
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins.
Weller et al., Farmington, United States. In J Virol, 2013
In fact, we learned that all 10 of the canonical ATR pathway proteins are stable in HSV-infected cells and are recruited to viral replication compartments; furthermore, short hairpin RNA (shRNA) knockdown shows that several, including ATRIP, RPA70, TopBP1, Claspin, and CINP, are required for efficient HSV-1 replication.
Association study of selected genetic polymorphisms and occurrence of venous thromboembolism in patients with multiple myeloma who were treated with thalidomide.
Hajek et al., Brno, Czech Republic. In Clin Lymphoma Myeloma Leuk, 2011
In our retrospective study, we analyzed candidate single-nucleotide polymorphisms (SNP), CINP (rs7011), CETP (rs289747), ALDH1A1 (rs610529), CDKN1A (rs3829963), GAN (rs2608555), vascular endothelial growth factor (rs699947), and ALDH1A1 (rs168351), previously identified in a large association study based on the hypothesis-driven candidate gene approach nominated by the International Myeloma Foundation "Bank On A Cure" (3404 SNPs).
Hepatitis C virus NS5B protein delays s phase progression in human hepatocyte-derived cells by relocalizing cyclin-dependent kinase 2-interacting protein (CINP).
Yuan et al., Shanghai, China. In J Biol Chem, 2011
NS5B delays cells in S phase through interaction with CINP and relocalization of the protein from the nucleus to the cytoplasm
[Danish pioneers of psychopharmacology].
Vestergaard, In Dan Medicinhist Arbog, 2010
Mogens Schou advocated throughout his long life for the benefits of lithium treatment for bipolar patients, Lars Gram for the use of drug monitoring in the pharmacological treatment of depressed patients, Erik Jacobsen invented Antabus for treatment of alcohol dependence and later became one of the first presidents of the Collegium Internationale Neuropsychopharmacologicum (CINP) and finally, Claus Braestrup was the first to describe the benzodiazepine receptor.
Functional genomic screens identify CINP as a genome maintenance protein.
Cortez et al., Nashville, United States. In Proc Natl Acad Sci U S A, 2009
CINP interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress, and G2 checkpoint integrity.
New therapeutic promises in the treatment of depression and schizophrenia.
Kulkarni et al., India. In Drug News Perspect, 2008
The XXVI Collegium Internationale Neuro-Psychopharmacologicum (CINP) Congress, commemorating its 50th anniversary, was held in Munich, Germany, from July 13 to 17, 2008, at the Internationales Congress Center.
A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes.
Lattes et al., Denver, United States. In Cell Cycle, 2005
CINP is part of the Cdc7-dependent mechanism of origin firing and a functional and physical link between Cdk2 and Cdc7 complexes at the origins
CINP 2000 - Collegium Internationale Neuro-Psychopharmacologicum 22nd Congress.
Ray, Leicester, United Kingdom. In Idrugs, 2000
At this large and varied meeting on neuropharmacotherapy, progress was reported on the newer more selective antipsychotics.
Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons.
Björklund et al., Lund, Sweden. In Eur J Neurosci, 1996
Neurotrophic effects of human brain-derived neurotrophic factor (hBDNF) on forebrain cholinergic neurons were addressed after ex vivo gene transfer to the intact adult rat brain, using a conditionally immortalized neural progenitor cell line (CINP) engineered to secrete the neurotrophin (2.8 ng/h/10(6) cells).
CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum.
Björklund et al., Lund, Sweden. In J Neurosci, 1995
A CNS-derived conditionally immortalized temperature-sensitive neural progenitor (CINP) cell line was used to generate NGF-secreting cells suitable for intracerebral transplantation.
Biological markers of depression: WHO multi-center studies and future perspective.
Yamashita et al., Sapporo, Japan. In Prog Neuropsychopharmacol Biol Psychiatry, 1991
20 papers related to markers of depression were presented at the 17th Congress of CINP, Kyoto, 1990.
share on facebooktweetadd +1mail to friends