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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Chromogranin B

chromogranin B, CgB, SGI, semenogelin, SG1, SEMG, semenogelin I
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009] (from NCBI)
Top mentioned proteins: CAN, HAD, chromogranin A, ACID, fibrillin-1
Papers on chromogranin B
Frequency of Aminoglycoside-Modifying Enzymes and ArmA Among Different Sequence Groups of Acinetobacter baumannii in Iran.
New
Goli et al., Tabrīz, Iran. In Microb Drug Resist, Feb 2016
The majority of isolates belonged to SG1 (39%), SG2 (33.3%), and SG3 (12.6%), whereas the remaining ones were assigned to six novel variants of SGs.
PROX1 promotes secretory granule formation in medullary thyroid cancer cells.
New
Kamma et al., Kami-renjaku, Japan. In Endocrinology, Feb 2016
Knockdown of PROX1 in an MTC cells reduced SGs detected by electron microscopy, and decreased expression of SG-related genes (Chromogranin A, Chromogranin B, Secretogranin II, Secretogranin III, Synaptophysin and Carboxypeptidase E).
The novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes.
New
Jang et al., Taegu, South Korea. In Int J Mol Med, Jan 2016
SGI-1776, an inhibitor of Pim kinases, is widely used to assess the physiological roles of Pim kinases, particularly cell functions.
Conformational analysis of champedak galactose-binding lectin under different urea concentrations.
New
Tayyab et al., Kuala Lumpur, Malaysia. In Plant Physiol Biochem, Jan 2016
Conformational analysis of champedak galactose-binding (CGB) lectin under different urea concentrations was studied in phosphate-buffered saline (pH 7.2) using far-ultraviolet circular dichroism (far-UV CD), tryptophan (Trp) fluorescence and ANS fluorescence.
Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours.
New
Darby et al., Salford, United Kingdom. In Clin Endocrinol (oxf), Dec 2015
OBJECTIVE: Chromogranin-A (CgA) and -B (CgB) are markers for monitoring disease status in patients with gastroenteropancreatic neuroendocrine tumours (NETs).
Evaluation of Human Semenogelin Membrane Strip Test for Species Cross-reactivity in Dogs.
New
Lanka et al., Urbana, United States. In Vet Pathol, Dec 2015
They also examined the distribution of human semenogelin I transcripts in the canine testis, prostate, and several bodily fluids by reverse transcription polymerase chain reaction.
Review: hCGs: different sources of production, different glycoforms and functions.
Review
New
Evain-Brion et al., Paris, France. In Placenta, Apr 2015
The hCG β-subunit contains two sites of N-glycosylation and four sites of O-glycosylation and is encoded by a cluster of genes (CGB).
Novel drugs for older patients with acute myeloid leukemia.
Review
New
Garcia-Manero et al., Houston, United States. In Leukemia, Apr 2015
Hypomethylating agents (azacitidine, decitabine, SGI-110), histone deacetylase inhibitors (vorinostat, pracinostat, panobinostat), FMS-like tyrosine kinase receptor-3 inhibitors (quizartinib, sorafenib, midostaurin, crenolanib), cytotoxic agents (clofarabine, sapacitabine, vosaroxin), cell cycle inhibitors (barasertib, volasertib, rigosertib) and monoclonal antibodies (gentuzumab ozogamicin, lintuzumab-Ac225) represent some of these promising new treatments.
Cross-reactions in IgM ELISA tests to Legionella pneumophila sg1 and Bordetella pertussis among children suspected of legionellosis; potential impact of vaccination against pertussis?
Pancer, Warsaw, Poland. In Cent Eur J Immunol, 2014
Sera were pre-absorbed with antigens of L. pneumophila sg1, B. pertussis or both, and tested by ELISA tests.
Problem of immunoglobulin M co-detection in serological response to bacterial and viral respiratory pathogens among children suspected of legionellosis.
Pancer, Warsaw, Poland. In Cent Eur J Immunol, 2014
In the prospective examinations (only Legionella pneumophila sg1), a positive level of IgM was found in 35 patients, but in 59 children together with retrospective tests.
Biochemical Testing in Patients with Neuroendocrine Tumors.
Review
Granberg, Uppsala, Sweden. In Front Horm Res, 2014
Nonfunctioning tumors can either secrete no hormones at all, or secrete hormones not giving rise to endocrine symptoms, such as chromogranin A, chromogranin B or pancreatic polypeptide.
The surging role of Chromogranin A in cardiovascular homeostasis.
Review
Cerra et al., Rende, Italy. In Front Chem, 2013
Together with Chromogranin B and Secretogranins, Chromogranin A (CGA) is stored in secretory (chromaffin) granules of the diffuse neuroendocrine system and released with noradrenalin and adrenalin.
DNA methyltransferase-1 inhibitors as epigenetic therapy for cancer.
Review
Capalash et al., Chandīgarh, India. In Curr Cancer Drug Targets, 2013
This review discusses nucleoside analogues (azacytidine, decitabine, zebularine, SGI-110, CP-4200), non-nucleoside ihibitors both synthetic (hydralazine, RG108, procaine, procainamide, IM25, disulfiram) and natural compounds (curcumin, genistein, EGCG, resveratrol, equol, parthenolide) which act through different mechanisms to inhibit DNMTs.
Chromogranins A and B are key proteins in amine accumulation, but the catecholamine secretory pathway is conserved without them.
GeneRIF
Borges et al., Santa Cruz de Tenerife, Spain. In Faseb J, 2012
Although chromogranins regulate the amine concentration in LDCVs, they are not completely essential.
C-terminal domain of chromogranin B regulates intracellular calcium signaling.
GeneRIF
Ehrlich et al., New Haven, United States. In J Biol Chem, 2012
C-terminal domain of chromogranin B regulates intracellular calcium signaling.
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.
GeneRIF
Greene et al., San Francisco, United States. In Cell Host Microbe, 2012
Peptides released by physiological cleavage of Semg1 and Semg2 form amyloids that enhance HIV infection.
The extended granin family: structure, function, and biomedical implications.
Review
Impact
Salton et al., Minneapolis, United States. In Endocr Rev, 2011
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) that together comprise the granin family subserve essential roles in the regulated secretory pathway that is responsible for controlled delivery of peptides, hormones, neurotransmitters, and growth factors.
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.
GeneRIF
Kolodkin et al., Baltimore, United States. In Neuron, 2011
Sema5A and Sema5B inhibit retinal neurite outgrowth through PlexinA1 and PlexinA3 receptors both in vitro and in vivo.
Expression of semenogelins I and II and its prognostic significance in human prostate cancer.
GeneRIF
Miyamoto et al., Rochester, United States. In Prostate, 2011
These results suggest the involvement of semenogelins in prostate cancer and their prognostic values in predicting cancer progression after radical prostatectomy.
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity.
Impact
Lahn et al., Chicago, United States. In Nat Genet, 2004
Specifically, we show that the evolution of SEMG2, the gene encoding semenogelin II, a main structural component of semen coagulum, is accelerated in polyandrous primates relative to monandrous primates.
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