Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS inductionmore suppliers
In Marine Drugs, 2011
... calreticulin(CALR), protein disulfide isomerase (PDI), Bax, Bcl-xL and Bcl-2, PERK, phospho-PERK (p-PERK), phospho-elF2α (p-elF2α) and CHOP were from Cell Signaling Technology (Danvers, MA, USA) ...
Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy.
Shijiazhuang, China. In Acta Pharmacol Sin, Jan 2016
By using different monomers and composite prescriptions of TCM, it is possible to modulate the ratio of Bcl-2/Bax, regulate the expression of caspase proteases and mitochondrial transmembrane potential, increase the expression of Fas and p53, down-regulate NF-κB pathway and the expression of CHOP and survivin, and block cell cycle progression.
Cell death induced by endoplasmic reticulum stress.
l'Hospitalet de Llobregat, Spain. In Febs J, Dec 2015
Central to the unfolded protein response are the sensors PERK, IRE1 and ATF6, as well as other signaling nodes such as c-Jun N-terminal kinase 1 (JNK) and the downstream transcription factors XBP1, ATF4 and CHOP.
Bortezomib-based therapy for newly diagnosed mantle-cell lymphoma.
Aş Şanamayn, Syria. In N Engl J Med, Apr 2015
We investigated whether substituting bortezomib for vincristine in frontline therapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) could improve outcomes in patients with newly diagnosed mantle-cell lymphoma.
Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions.
More papers using
Riyadh, Saudi Arabia. In Adv Hematol, 2014
Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP-like regimens have been the backbone while more intensive regimens such as cyclophosphamide, vincristine, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, high-dose cytarabine (CODOX-M/IVAC), or dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (DA-EPOCH) are possible options.
Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma
In Cell Death & Disease, 1994
... cleaved forms; 1:200, IMG-273, IMGENEX, San Diego, CA, USA), anti-Bip (1:500, #3177, Cell Signaling Technology), anti-CHOP (1:200, sc-575, Santa Cruz Biotechnology), anti- ...