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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Cholecystokinin A receptor

cholecystokinin receptor, CCK-XLR
Top mentioned proteins: Cholecystokinin, HAD, ACID, CAN, Gastrin
Papers on cholecystokinin receptor
Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.
Miller et al., Scottsdale, United States. In J Med Chem, Jan 2016
The type 1 cholecystokinin receptor (CCK1R) has multiple physiologic roles relating to nutrient homeostasis, including mediation of postcibal satiety.
Two cholecystokinin receptor subtypes are identified in goldfish, being the CCKAR involved in the regulation of intestinal motility.
Delgado et al., Madrid, Spain. In Comp Biochem Physiol A Mol Integr Physiol, Sep 2015
Partial-length mRNAs encoding two CCK receptor isoforms (CCKAR and CCKBR.I) were sequenced and the structural analysis showed that both receptors belong to the G-protein coupled receptor superfamily.
Association of single-nucleotide polymorphism of cholecystokinin receptor A gene with schizophrenia in an Eastern Indian population.
Basu et al., Calcutta, India. In Indian J Psychiatry, Jul 2015
CONTEXT: Cholecystokinin A receptor (CCK-AR) gene polymorphism is being increasingly reported in schizophrenia.
Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.
Aragay et al., Barcelona, Spain. In J Biol Chem, Jul 2015
Utilizing multiple methods, we have identified Rgnef as a new effector for Gα13 downstream of gastrin and the type 2 cholecystokinin receptor.
Elimination of a cholecystokinin receptor agonist 'trigger' in an effort to develop positive allosteric modulators without intrinsic agonist activity.
Miller et al., Scottsdale, United States. In Bioorg Med Chem Lett, Jun 2015
Cholecystokinin (CCK) acts at the type 1 cholecystokinin receptor (CCK1R) to elicit satiety and is a well-established drug target for obesity.
Changes in ghrelin, CCK, GLP-1, and peroxisome proliferator-activated receptors in a hypoxia-induced anorexia rat model.
Singh et al., Delhi, India. In Endokrynol Pol, 2014
Stomach cholecystokinin receptor (CCKAR), PPARα, and PPARδ decreased.
The radiometal makes a difference. Synthesis and preliminary characterisation of DOTA-minigastrin analogue complexes with Ga, Lu and Y.
Mikołajczak et al., In Nucl Med Rev Cent East Eur, 2014
So far, there are no such studies for the ligands of gastrin/cholecystokinin receptor CCK2R.
The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms.
Lægreid et al., Trondheim, Norway. In Bmc Syst Biol, 2014
These proteins represent experimentally testable hypotheses for gaining new knowledge on gastrin- and cholecystokinin receptor signaling.
Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis.
Chiba et al., Kyoto, Japan. In Immunity, 2012
Pancreatitis induced by high-dose cerulein (a cholecystokinin receptor agonist) administration depends on NOD1 stimulation by gut microflora.
[The role of feeding behaviour hormones in the development of cholelithiasis].
Iamlikhanova et al., In Eksp Klin Gastroenterol, 2011
Leptin regulates the expression of genes responsible for the pathogenesis of cholesterol GSD -cholecystokinin receptor gene A, acetylcholine receptor beta2, Ca-calmodulin-dependent protein kinase, mucin3, carboxylesterazy, HMG-CoA reductase.
Therapeutic potential for novel drugs targeting the type 1 cholecystokinin receptor.
Miller et al., Scottsdale, United States. In Br J Pharmacol, 2010
Cholecystokinin (CCK) is a physiologically important gastrointestinal and neuronal peptide hormone, with roles in stimulating gallbladder contraction, pancreatic secretion, gastrointestinal motility and satiety.
Milestones in the Activation of a G Protein-Coupled Receptor. Insights from Molecular-Dynamics Simulations into the Human Cholecystokinin Receptor-1.
Chipot, Vandœuvre-lès-Nancy, France. In J Chem Theory Comput, 2009
A model of the human cholecystokinin receptor-1 (CCK1R) has been proposed recently.
The production and role of gastrin-17 and gastrin-17-gly in gastrointestinal cancers.
Lovas et al., Omaha, United States. In Protein Pept Lett, 2008
Additionally, gastrin has been suspected to play a role in the formation and growth of cancers of the colon, but recent studies have instead implicated gastrin processing intermediates, such as gastrin-17-Gly, acting upon a putative, non-cholecystokinin receptor.
Genetic determination of irritable bowel syndrome.
Dumitrascu et al., Cluj-Napoca / Kolozsvár, Romania. In World J Gastroenterol, 2008
Whereas no specific gene has been identified in association with IBS, recent studies have noticed the importance of polymorphisms in the promoter region of the serotonin reuptake transporter gene, G-protein beta 3 subunit gene (C825T), cholecystokinin receptor (CCKAR gene 779T>C), and high-producer tumor necrosis factor genotype.
Structural basis of cholecystokinin receptor binding and regulation.
Gao et al., Scottsdale, United States. In Pharmacol Ther, 2008
Two structurally-related guanine nucleotide-binding protein-coupled receptors for two related peptides, cholecystokinin (CCK) and gastrin, have evolved to exhibit substantial diversity in specificity of ligand recognition, in their molecular basis of binding these ligands, and in their mechanisms of biochemical and cellular regulation.
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