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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


CHODL, chondrolectin, C21orf68, PRED12
This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] (from NCBI)
Top mentioned proteins: OUT, layilin, CAN, GC-rich sequence DNA-binding factor candidate GCFC, TAK1L
Papers on CHODL
Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy.
Talbot et al., Oxford, United Kingdom. In Hum Mol Genet, 2014
Here, we have performed functional studies of one of these genes, chondrolectin (Chodl), known to be highly expressed in motor neurons and important for correct motor axon outgrowth in zebrafish.
Chondrolectin mediates growth cone interactions of motor axons with an intermediate target.
Becker et al., Edinburgh, United Kingdom. In J Neurosci, 2012
The C-type lectin chondrolectin (chodl) represents one of the major gene products dysregulated in spinal muscular atrophy models in mice.
Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Daigo et al., Tokyo, Japan. In Clin Cancer Res, 2012
Data indicate that chondrolectin (CHODL) is likely to be a prognostic biomarker in the clinic and targeting CHODL might be a strategy for the development of anticancer drugs.
Identification of novel spinal cholinergic genetic subtypes disclose Chodl and Pitx2 as markers for fast motor neurons and partition cells.
Kullander et al., Uppsala, Sweden. In J Comp Neurol, 2010
Further, we present evidence that chondrolectin (Chodl) is expressed by fast motor neurons and that estrogen-related receptor beta (ERRbeta) is a candidate marker for slow motor neurons.
The cytoplasmic domain of chondrolectin interacts with the beta-subunit of Rab geranylgeranyl transferase.
Merregaert et al., Antwerp, Belgium. In Cell Mol Biol Lett, 2007
Mouse chondrolectin (chodl) was isolated out of the tail tip of four-day old 129/SvJ mice as a by-product of a PCR-based subtractive cDNA library screening.
Expression and localization of CHODLDeltaE/CHODLfDeltaE, the soluble isoform of chondrolectin.
Merregaert et al., Edegem, Belgium. In Cell Biol Int, 2007
CHODLDeltaE/CHODLfDeltaE protein variant localizes in the late endoplasmic reticulum and is detected in spleen and tonsils; the isoform seems to be differentially expressed in thymocytes and lymphocytes.
A novel alternative spliced chondrolectin isoform lacking the transmembrane domain is expressed during T cell maturation.
Merregaert et al., Edegem, Belgium. In J Biol Chem, 2003
study describes the molecular characterization of novel members of the chondrolectin family associated with T cell maturation and a subcellular localization of chondrolectin f isoform in the endoplasmic reticulum-Golgi apparatus
Isolation and characterization of chondrolectin (Chodl), a novel C-type lectin predominantly expressed in muscle cells.
Merregaert et al., Antwerp, Belgium. In Gene, 2003
In this study, we identified and characterized the mouse orthologue of the human chondrolectin gene, Chodl.
Molecular cloning and characterization of human chondrolectin, a novel type I transmembrane protein homologous to C-type lectins.
Merregaert et al., Antwerp, Belgium. In Genomics, 2002
cloning and characterization; localized at chromosome 21q21
From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map.
Antonarakis et al., Genève, Switzerland. In Genomics, 2001
In contrast, PRED12 (now called C21orf68) and PRED34 (C21orf63) are now confirmed transcripts.
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