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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Chordin-like 2

CHL2, BNF1, chordin-like 2, breast tumor novel factor 1, Chrdl2
Top mentioned proteins: AGE, Chordin, CAN, Chl, cardiotrophin-1
Papers on CHL2
Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage.
Henning et al., Chapel Hill, United States. In Cell Tissue Res, Aug 2015
Of these, the epidermal growth factor (EGF) family member amphiregulin and the BMP antagonist chordin-like 2 were chosen for further study.
Serum cytokine profile in patients with pancreatic cancer.
Linares et al., Granada, Spain. In Pancreas, 2014
Besides, the cytokines CD30 ligand/tumor necrosis factor superfamily, member 8 (TNFSF8), chordin-like 2, FGF-10/KGF-2, growth/differentiation factor 15, I-TAC/CXCL11, OSM, and SCF were differentially expressed in response to treatment.
Cloning of catechol 2,3-dioxygenase gene and construction of a stable genetically engineered strain for degrading crude oil.
Chen et al., Xi'an, China. In Indian J Microbiol, 2014
Pseudomonas putida strain BNF1 was isolated to degrade aromatic hydrocarbons efficiently and use phenol as a main carbon and energy source to support its growth.
Transcriptome analysis of the dihydrotestosterone-exposed fetal rat gubernaculum identifies common androgen and insulin-like 3 targets.
McCahan et al., Wilmington, United States. In Biol Reprod, 2013
The qRT-PCR results confirmed that DHT increased expression of the INSL3-responsive genes Crlf1 and Chrdl2 but reduced expression of Wnt4.
Exercise training attenuates aging-associated mitochondrial dysfunction in rat skeletal muscle: role of PGC-1α.
Ji et al., Minneapolis, United States. In Exp Gerontol, 2013
Three groups of Fischer 344/BNF1 rats were used: young, sedentary (Y, 4 months); old, sedentary (O, 22 months); and old trained (OT, 22 months), subjected to treadmill running at 17.5 m/min, 10% grade for 45 min/day, 5 days/week for 12-weeks.
Microarray expression analysis of genes and pathways involved in growth plate cartilage injury responses and bony repair.
Xian et al., Adelaide, Australia. In Bone, 2012
Four major functional groupings of differentially expressed genes with known roles in skeletal development were identified across the time-course of bone bridge formation, including Wnt signalling (SFRP1, SFRP4, β-catenin, Csnk2a1, Tcf7, Lef1, Fzd1, Fzd2, Wisp1 and Cpz), BMP signalling (BMP-2, BMP-6, BMP-7, Chrd, Chrdl2 and Id1), osteoblast differentiation (BMP-2, BMP-6, Chrd, Hgn, Spp1, Axin2, β-catenin, Bglap2) and skeletal development (Chrd, Mmp9, BMP-1, BMP-6, Spp1, Fgfr1 and Traf6).
The effect of aging on the density of the sensory nerve fiber innervation of bone and acute skeletal pain.
Mantyh et al., Tucson, United States. In Neurobiol Aging, 2012
To determine whether the density of sensory nerve fibers that transduce skeletal pain changes with age, calcitonin gene related peptide (CGRP) and neurofilament 200 kDa (NF200) sensory nerve fibers that innervate the femur were examined in the femurs of young (4-month-old), middle-aged (13-month-old) and old (36-month-old) male F344/BNF1 rats.
Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.
Neri et al., Paris, France. In Bmc Genomics, 2011
Finally, 49 modifiers of 128Q-neuron dysfunction that are dysregulated in the striatum of either R/2 or CHL2 HD mice, or both, were identified.
Age-related retention of fiber cell nuclei and nuclear fragments in the lens cortices of multiple species.
Wolf et al., Seattle, United States. In Mol Vis, 2010
However, a second rat strain, BNF1, in which opacity was quite high had no increase in retained nuclei with age nor did any of the old monkeys, indicating that retained nuclei could not be a cause of opacity in these animals.
Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways.
Barthold et al., Wilmington, United States. In Biol Reprod, 2010
Using quantitative RT-PCR, the microarray data were confirmed, and the induction of Bmp3, Chrdl2, Crlf1, Nptx2, Pnoc, Wnt4, and Wnt5a mRNA levels were examined over a range of INSL3 concentrations (0.1-100 nM) in male and female gubernaculum.
Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis.
Greenspan et al., Madison, United States. In Dev Biol, 2010
The chl gene is on a region of chromosome 21 syntenic with the area of murine chromosome 7 bearing the CHL2 gene.
Comparison between colorectal low- and high-grade mucinous adenocarcinoma with MUC1 and MUC5AC.
Tsujimura et al., Nishinomiya, Japan. In World J Gastrointest Oncol, 2009
Immunohistochemically, the expression of 2 types of MUC1 (MUC1/DF and MUC1/CORE), MUC2, 2 types of MUC5AC (MUC5AC/CHL2 and HGM), MUC6, CDX2, and CD10 was examined in 16 cases of MAC consisting of 6 low- and 10 high-grade types.
The binding of von Willebrand factor type C domains of Chordin family proteins to BMP-2 and Tsg is mediated by their SD1 subdomain.
Zhang et al., Würzburg, Germany. In Biochem Biophys Res Commun, 2009
Now the SD1 from VWC1 and VWC3 of Chordin and CHL2 were established to confer BMP affinity and specificity to these proteins also.
Interaction of amphiphilic chlorin-based photosensitizers with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine monolayers.
Rogalska et al., Vandœuvre-lès-Nancy, France. In Chem Phys Lipids, 2009
Here, the interaction between 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers used as model membranes, and three different photosensitizers were studied; the derivatives were the non-conjugated meta-tetrahydroxyphenylchlorin (m-THPC, CHL1) and tris(3-hydroxyphenyl)-4-carboxyphenylchlorin (CHL2), as well as a folic acid-conjugated m-THPC-like molecule (CHL3).
Candidate genes responsible for common and different pathology of infected muscle tissues between Trichinella spiralis and T. pseudospiralis infection.
Takahashi et al., Gifu, Japan. In Parasitol Int, 2008
Many of these differentially expressed genes were associated with satellite cell activation and proliferation (paired box gene 7, Pax7; Pax3; desmin; M-cadherin), myogenesis and muscle development (eyes absent 2 homolog, Eya2; myocyte enhancer factor 2C, MEF2C; pre B-cell leukemia transcription factor 1, Pbx1; chordin-like 2, Chrdl2), cell differentiation (galectin 1; insulin like growth factors, IGFs; c-ski; msh-like 1, Msx1; Numb), cell proliferation and cycle regulation (retinoblastoma 1, Rb1; granulin; p21, CDK4, cyclin A2), and apoptosis (tumor necrosis factor receptor 1, TNF-R1; programmed cell death protein 11, Pdcd11; Pdcd1; nuclear protein 1, Nuprl; clusterin, CLU).
hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
Rotman et al., Tel Aviv-Yafo, Israel. In Gene, 2004
Differential expression of CHL2 variants was observed during myoblast and osteoblast differentiation, implying a role for this gene in these physiological processes.
A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.
Zhang et al., Thousand Oaks, United States. In Development, 2004
CHL2 expression is restricted to chondrocytes of various developing joint cartilage surfaces and connective tissues in reproductive organs.
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