Novel endogenous angiogenesis inhibitors and their therapeutic potential.
Singapore, Singapore. In Acta Pharmacol Sin, Oct 2015
In this review, we highlight ten novel endogenous protein angiogenesis inhibitors discovered within the last five years, including ISM1, FKBPL, CHIP, ARHGAP18, MMRN2, SOCS3, TAp73, ZNF24, GPR56 and JWA.
A CHIPotle in physiology and disease.
Calcutta, India. In Int J Biochem Cell Biol, 2015
The carboxy-terminus of Hsc70 interacting protein (CHIP) is known to function as a chaperone associated E3 ligase for several proteins and regulates a variety of physiological processes.
CHIP: a co-chaperone for degradation by the proteasome.
Grahamstown, South Africa. In Subcell Biochem, 2014
Similar to folding complexes, the ability of chaperones to mediate protein degradation is regulated by co-chaperones, such as the C terminal Hsp70 binding protein (CHIP).
The E3 ligase CHIP: insights into its structure and regulation.
Calcutta, India. In Biomed Res Int, 2013
The carboxy-terminus of Hsc70 interacting protein (CHIP) is a cochaperone E3 ligase containing three tandem repeats of tetratricopeptide (TPR) motifs and a C-terminal U-box domain separated by a charged coiled-coil region.