Key players of singlet oxygen-induced cell death in plants.
Marseille, France. In Front Plant Sci, 2014
However, during the last 15 years, the isolation and characterization of two (1)O2-overproducing mutants in Arabidopsis thaliana, flu and ch1, has allowed the identification of genetically controlled (1)O2 cell death pathways and a (1)O2 acclimation pathway that are triggered at sub-cytotoxic concentrations of (1)O2.
Tregitope update: mechanism of action parallels IVIg.
Providence, United States. In Autoimmun Rev, 2013
By comparing the human IgG Tregitopes (hTregitopes 167 and 289, located in the IgG CH1 and CH2 domains) and Fab to murine sequences, we identified class II-restricted murine Tregitope homologs (mTregitopes).
Radioiodinated anti-TAG-72 humanized CH2 domain-deleted antibody
Bethesda, United States. In Unknown Journal, 2007
The light chain constant domain was a human Cκ, and the human γ1 chain was genetically modified to produce a heavy chain composed of a CH1 domain followed by a partial IgG1 hinge region tethered to the CH3 heavy chain domain by addition of a flexible 10-amino-acid GGGSSGGGSG spacer (22).