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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

GULP, engulfment adaptor PTB domain containing 1

CED-6, GULP, GULP1, hCED-6
The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011] (from NCBI)
Papers on CED-6
Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.
GeneRIF
Kiss et al., Montréal, Canada. In J Biol Chem, 2012
GULP expression positively regulates TGF-beta signaling leading to growth inhibition, this may represent an attractive target to achieve TGF-beta responsiveness in ovarian cells.
The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.
GeneRIF
Traub et al., Pittsburgh, United States. In Mol Biol Cell, 2012
The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.
Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein.
GeneRIF
von Arnim et al., Ulm, Germany. In Neurobiol Aging, 2012
This study identify GULP1 as a novel neuronal amyloid-beta precursor protein interacting protein that alters trafficking and processing of amyloid-beta precursor protein.
GULP1 is a novel APP-interacting protein that alters APP processing.
GeneRIF
Lau et al., Hong Kong, Hong Kong. In Biochem J, 2011
overexpression of GULP1 enhanced the generation of APP CTFs (C-terminal fragments) and Abeta, whereas knockdown of GULP1 suppressed APP CTFs and Abeta production.
Adaptor protein GULP is involved in stabilin-1-mediated phagocytosis.
GeneRIF
Kim et al., Kyŏngju, South Korea. In Biochem Biophys Res Commun, 2010
these results indicate that GULP functions as an adaptor protein for stabilin-1-mediated phagocytosis.
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