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Carcinoembryonic antigen-related cell adhesion molecule 5

CEA, Carcinoembryonic antigen
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] (from NCBI)
Top mentioned proteins: CAN, HAD, AGE, V1a, cytokeratin
Papers using CEA antibodies
Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
Supplier
Margel Shlomo et al., In Journal of Nanobiotechnology, 2010
... Haemek, Israel; LS174t and HT29 tumor cell lines from American Type Culture Collection (ATCC); monoclonal anti-CEA (T86-66) and anti-TAG-72 (CC-49) antibodies were purified from the hybridoma supernatant at Alomone Labs, Israel; human bowel juice ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
Supplier
Paul Marinus A. et al., In Pathology Research International, 1998
... E12, CK14 (Neomarkers), CK19, EMA, CEA (BioGenex), TTF-1, SP-A, CD56 (Novocastra), ...
Biliary Glycoprotein Messenger-Rna Expression Is Increased in Primary Lung-Cancer, Especially in Squamous-Cell Carcinoma.
Supplier
Navarro Alfons, In PLoS ONE, 1993
... Anti-human CEA/CEACAM5 mAb clone CI-P83-1 was obtained from Dianova (Hamburg, Germany) ...
Papers on CEA
EGFR mutation status in plasma and tumor tissues in non-small cell lung cancer serves as a predictor of response to EGFR-TKI treatment.
New
Wang et al., Chongqing, China. In Cancer Biol Ther, 19 Feb 2016
The gender and tumor histology of patients served as independent predictors of EGFR mutations in both tumor tissues and plasma, while CEA level was an independent predictor of EGFR mutations in the plasma.
Serum uric acid as a surrogate marker of favorable response to bevacizumab treatment in patients with metastatic colon cancer.
New
Mandel et al., İstanbul, Turkey. In Clin Transl Oncol, 19 Feb 2016
The decline of CEA level was related to uric acid level (p < 0.022).
Musashi2 as a novel predictive biomarker for liver metastasis and poor prognosis in colorectal cancer.
New
Chen et al., Guangzhou, China. In Cancer Med, 18 Feb 2016
Overexpression of MSI-2 was associated with depth of invasion, lymph node metastasis, distant metastasis, liver metastasis, Tumor Node Metastasis (TNM) clinical stage, and Carcinoembryonicantigen (CEA) level (P = 0.040, 0.014, <0.001, <0.001, 0.003, and 0.002, respectively).
Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: a comparative study.
New
Egevad et al., Stockholm, Sweden. In Apmis, 17 Feb 2016
Slides were stained for estrogen, progesterone and androgen receptor, prolactin, PSA, prostein, PSMA, PSAP, CDX2, lysozyme, villin, monoclonal CEA, CK7, CK20, HMWCK, p63, p504s, c-Myc, EGFR, Ki-67, p16, p21, p27, p53, PTEN, ERG, and PAX-8.
Monitoring the treatment outcome in endometrial cancer patients by CEA and TATI.
New
Stefaniak et al., Warsaw, Poland. In Tumour Biol, 16 Feb 2016
UNASSIGNED: An attempt was made to compare the usefulness of determining markers carcinoembryonic antigen (CEA) and tumor-associated trypsin inhibitor (TATI) in endometrial cancer patients in whom recurrence or distant metastasis was diagnosed in observation after treatment.
Evaluating the Prognostic Role of Elevated Preoperative Carcinoembryonic Antigen Levels in Colon Cancer Patients: Results from the National Cancer Database.
New
Fleming et al., Rochester, United States. In Ann Surg Oncol, 12 Feb 2016
OBJECTIVES: Carcinoembryonic antigen (CEA) is a reliable tumor marker for the management and surveillance of colon cancer.
Ethanol-induced anxiolysis and neuronal activation in the amygdala and bed nucleus of the stria terminalis.
New
Wilson et al., Columbia, United States. In Alcohol, 26 Dec 2015
Our results suggest that activation of the CeA and BNST are involved in the behavioral expression of ethanol-induced anxiolysis, and that differences in basal anxiety state may be correlated with NPY systems in the extended amygdala.
Htr2a-Expressing Cells in the Central Amygdala Control the Hierarchy between Innate and Learned Fear.
New
Impact
Kobayakawa et al., Ōsaka, Japan. In Cell, 19 Dec 2015
Whole-brain mapping and pharmacological screening indicated that serotonin-2A receptor (Htr2a)-expressing cells in the central amygdala (CeA) control both innate and learned freezing, but in opposing directions.
[Determination of CEA, EGFR and hTERT expression in peritoneal lavage in patients with pancreatic adenocarcinoma using RT - PCR method].
New
Loveček et al., In Rozhl Chir, Nov 2015
INTRODUCTION: The aim of this study is to assess the significance of CEA, EGFR and hTERT as markers of occult tumor cells for predicting treatment outcomes in pancreatic cancers, as well as determining the cut-off values of these markers individually in peritoneal lavage.
Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline.
New
Impact
Harris et al., Ann Arbor, United States. In J Clin Oncol, Sep 2015
Carcinoembryonic antigen, cancer antigen 15-3, and cancer antigen 27-29 may be used as adjunctive assessments, but not alone, to contribute to decisions regarding therapy.
Prognostic significance of Glasgow prognostic score in patients with stage II colorectal cancer.
Yu et al., Taizhou, China. In Int J Clin Exp Med, 2014
Increased preoperative GPS was found associated with elevated carcinoembryonic antigen (CEA) and decreasing of KPS.
Value of serum marker HE4 in pulmonary carcinoma diagnosis.
Sun et al., Yancheng, China. In Int J Clin Exp Med, 2014
Serum levels of carcinoma embryonic antigen (CEA), cytokeratin protein fragment 21-1 (CYFRA21-1), neuron-specific enolase (NSE), and human epididymis protein 4 (HE4) were detected using electrochemiluminescence.
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data.
Impact
Michiels et al., Paris, France. In Lancet Oncol, 2014
Carcinoembryonic antigen and cancer antigen 15-3 concentrations at baseline and during therapy did not add significant information to the best baseline model.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Impact
Blumberg et al., Boston, United States. In Immunity, 2012
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on activated T cells and signals through either a long (L) cytoplasmic tail containing immune receptor tyrosine based inhibitory motifs, which provide inhibitory function, or a short (S) cytoplasmic tail with an unknown role.
HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens.
GeneRIF
Hauck et al., Konstanz, Germany. In Arch Biochem Biophys, 2012
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
No correlation between pretreatment serum CEA levels and tumor volume in locally advanced rectal cancer patients.
GeneRIF
Kim et al., South Korea. In Clin Chim Acta, 2012
a positive correlation between CEA levels and survival
Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal cancer.
GeneRIF
Zhang et al., Harbin, China. In Onkologie, 2011
CEA mRNA, CK20 mRNA, and serum CEA than patients at stages I-III.
Efficacy of carcinogenic embryonic antigen in differential diagnosis of diseases of pancreas and liver--a comparative study in a tertiary care hospital of Western Nepal.
GeneRIF
Yadav et al., Pokhara, Nepal. In Asian Pac J Cancer Prev, 2011
High levels of carcinogenic embryonic antigen are associated with advanced stage of diseases of pancreas and liver.
Oxytocin selectively gates fear responses through distinct outputs from the central amygdala.
Impact
Stoop et al., Lausanne, Switzerland. In Science, 2011
Central amygdala (CeA) projections to hypothalamic and brain stem nuclei regulate the behavioral and physiological expression of fear, but it is unknown whether these different aspects of the fear response can be separately regulated by the CeA.
Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA.
GeneRIF
Feng et al., Xi'an, China. In World J Surg Oncol, 2010
High CEACAM7 is associated with gastric carcinoma.
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