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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Mar 2014.

Carcinoembryonic antigen-related cell adhesion molecule 5

CEA, Carcinoembryonic antigen
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, cytokeratin, p53
Papers using CEA antibodies
Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
Supplier
Margel Shlomo et al., In Journal of Nanobiotechnology, 2010
... Haemek, Israel; LS174t and HT29 tumor cell lines from American Type Culture Collection (ATCC); monoclonal anti-CEA (T86-66) and anti-TAG-72 (CC-49) antibodies were purified from the hybridoma supernatant at Alomone Labs, Israel; human bowel juice ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
Supplier
Paul Marinus A. et al., In Pathology Research International, 1998
... E12, CK14 (Neomarkers), CK19, EMA, CEA (BioGenex), TTF-1, SP-A, CD56 (Novocastra), ...
Biliary Glycoprotein Messenger-Rna Expression Is Increased in Primary Lung-Cancer, Especially in Squamous-Cell Carcinoma.
Supplier
Navarro Alfons, In PLoS ONE, 1993
... Anti-human CEA/CEACAM5 mAb clone CI-P83-1 was obtained from Dianova (Hamburg, Germany) ...
Papers on CEA
NEDD9 overexpression correlates with poor prognosis in gastric cancer.
New
Cai et al., Nantong, China. In Tumour Biol, 25 Apr 2014
The upregulated NEDD9 expression in gastric cancer tissue was significantly correlated with high preoperative CEA level (P = 0.044), poor differentiation (P = 0.007), tissue invasion (P = 0.015), present lymph node metastasis (P < 0.001), and high TNM stage (P < 0.001).
Innate Immune Factors Modulate Ethanol Interaction with GABAergic Transmission in Mouse Central Amygdala.
New
Siggins et al., Austin, United States. In Brain Behav Immun, 24 Apr 2014
We used intracellular recording of evoked GABAergic inhibitory postsynaptic potentials (eIPSPs) in central amygdala (CeA) neurons to examine the role of TLR4 activation by lipopolysaccharide (LPS) and deletion of its adapter protein CD14 in acute ethanol effects on the GABAergic system.
Involvement of amygdaloid neuropeptide Y in the anxiolytic effects of acupuncture during ethanol withdrawal in rats.
New
Zhao et al., Mudanjiang, China. In Neurosci Lett, 24 Apr 2014
UNLABELLED: The role of neuropeptide Y (NPY) in the central nucleus of amygdala (CeA) in the preventive effects of acupuncture against ethanol withdrawal-induced anxiety was investigated.
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data.
New
Impact
Michiels et al., Paris, France. In Lancet Oncol, 10 Apr 2014
Carcinoembryonic antigen and cancer antigen 15-3 concentrations at baseline and during therapy did not add significant information to the best baseline model.
Aptamers directly radiolabeled with technetium-99m as a potential agent capable of identifying carcinoembryonic antigen (CEA) in tumor cells T84.
New
Andrade et al., Belo Horizonte, Brazil. In Bioorg Med Chem Lett, 02 Apr 2014
Two aptamers (Apt3 and Apt3-amine) selected against the carcinoembryonic antigen (CEA) were used.
Significance of combined detection of LunX mRNA and tumor markers in diagnosis of lung carcinoma.
New
Zhou et al., Xinhui, China. In Chin J Cancer Res, 28 Feb 2014
OBJECTIVE: To evaluate the significance of combined detection of LunX mRNA, carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), and cytokeratin 21-1 fragment (CYFRA21-1) in clinical diagnosis of lung carcinoma.
Serum markers in small cell lung cancer: opportunities for improvement.
Review
New
Ramaekers et al., Maastricht, Netherlands. In Biochim Biophys Acta, Dec 2013
In this review the current status of these potential markers, like CEA, NSE, ProGRP, CK-BB, SCC, CgA, NCAM and several cytokeratins will be critically analyzed with respect to their performance in blood based assays.
The role of tumor markers and biomarkers in colorectal cancer.
Review
New
Krasnodebski et al., In Neoplasma, Dec 2013
Carcinoembryonic antigen still remains the only tumor marker of recognised efficacy in monitoring patients during and after CRC therapy.
Sclerosing polycystic adenosis of salivary glands: a review with some emphasis on intraductal epithelial proliferations.
Review
New
Petersson, Singapore, Singapore. In Head Neck Pathol, Jul 2013
CEA, p53 and HER2 is reportedly negative.
Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise.
Review
New
Hodge et al., Bethesda, United States. In Expert Rev Vaccines, Jun 2013
Concurrent with the US FDA's approval of the first therapeutic cancer vaccine, and supported by mounting clinical evidence indicating that targeting carcinoembryonic antigen (CEA) can safely overcome pre-existing tolerance, a multitude of novel CEA cancer vaccines are now in various stages of development.
[A novel screening method to establish tumor-targeting antibodies reliable for drug delivery system].
Review
Kato, Kawagoe, Japan. In Yakugaku Zasshi, 2012
Within these mAbs, we have identified tumor cell target molecules including not only carcinoembryonic antigen (CEA), epithelial cell adhesion molecule (EpCAM), epidermal growth factor receptor (EGFR), prostate specific membrane antigen (PSMA) but also novel tumor surface target molecules such as phosphatidic acid phosphatase type 2a (PAP2a) and interleukin-13 receptor variant α2 (IL-13Rα2) as tumor antigens.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Impact
Blumberg et al., Boston, United States. In Immunity, 2012
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on activated T cells and signals through either a long (L) cytoplasmic tail containing immune receptor tyrosine based inhibitory motifs, which provide inhibitory function, or a short (S) cytoplasmic tail with an unknown role.
HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens.
Review
GeneRIF
Hauck et al., Konstanz, Germany. In Arch Biochem Biophys, 2012
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
No correlation between pretreatment serum CEA levels and tumor volume in locally advanced rectal cancer patients.
GeneRIF
Kim et al., South Korea. In Clin Chim Acta, 2012
a positive correlation between CEA levels and survival
Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal cancer.
GeneRIF
Zhang et al., Harbin, China. In Onkologie, 2011
CEA mRNA, CK20 mRNA, and serum CEA than patients at stages I-III.
Efficacy of carcinogenic embryonic antigen in differential diagnosis of diseases of pancreas and liver--a comparative study in a tertiary care hospital of Western Nepal.
GeneRIF
Yadav et al., Pokhara, Nepal. In Asian Pac J Cancer Prev, 2011
High levels of carcinogenic embryonic antigen are associated with advanced stage of diseases of pancreas and liver.
Oxytocin selectively gates fear responses through distinct outputs from the central amygdala.
Impact
Stoop et al., Lausanne, Switzerland. In Science, 2011
Central amygdala (CeA) projections to hypothalamic and brain stem nuclei regulate the behavioral and physiological expression of fear, but it is unknown whether these different aspects of the fear response can be separately regulated by the CeA.
Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA.
GeneRIF
Feng et al., Xi'an, China. In World J Surg Oncol, 2010
High CEACAM7 is associated with gastric carcinoma.
Encoding of conditioned fear in central amygdala inhibitory circuits.
Impact
Lüthi et al., Basel, Switzerland. In Nature, 2010
The central amygdala (CEA), a nucleus predominantly composed of GABAergic inhibitory neurons, is essential for fear conditioning.
Carcinoembryonic antigen-related cell adhesion molecule-1 regulates granulopoiesis by inhibition of granulocyte colony-stimulating factor receptor.
Impact
Shively et al., Duarte, United States. In Immunity, 2010
Although carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is an activation marker for neutrophils and delays neutrophil apoptosis, the role of CEACAM1 in granulopoiesis and neutrophil-dependent host immune responses has not been investigated.
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