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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 22 Nov 2014.

Carcinoembryonic antigen-related cell adhesion molecule 5

CEA, Carcinoembryonic antigen
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, cytokeratin, V1a
Papers using CEA antibodies
Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
Supplier
Margel Shlomo et al., In Journal of Nanobiotechnology, 2010
... Haemek, Israel; LS174t and HT29 tumor cell lines from American Type Culture Collection (ATCC); monoclonal anti-CEA (T86-66) and anti-TAG-72 (CC-49) antibodies were purified from the hybridoma supernatant at Alomone Labs, Israel; human bowel juice ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
Supplier
Paul Marinus A. et al., In Pathology Research International, 1998
... E12, CK14 (Neomarkers), CK19, EMA, CEA (BioGenex), TTF-1, SP-A, CD56 (Novocastra), ...
Biliary Glycoprotein Messenger-Rna Expression Is Increased in Primary Lung-Cancer, Especially in Squamous-Cell Carcinoma.
Supplier
Navarro Alfons, In PLoS ONE, 1993
... Anti-human CEA/CEACAM5 mAb clone CI-P83-1 was obtained from Dianova (Hamburg, Germany) ...
Papers on CEA
Serum transforming growth factor-beta1 levels may have predictive and prognostic roles in patients with gastric cancer.
New
Duranyildiz et al., İstanbul, Turkey. In Tumour Biol, 13 Dec 2014
The known clinical variables including age of patient, gender, site of lesion, histology, histological grade, stage of disease, and serum levels of lactate dehydrogenase (LDH), CEA, and carbohydrate antigen (CA) 19.9 were not found to be correlated with serum TGF-beta1 concentrations (p > 0.05).
Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a cancer vaccine.
New
Hodge et al., In J Transl Med, 13 Dec 2014
Combining immunotherapy with targeted agents that have immunomodulatory capabilities could significantly improve its efficacy.MethodsWe evaluated the ability of cabozantinib, a receptor tyrosine kinase inhibitor, to modulate the immune system in vivo as well as alter the phenotype of tumor cells in vitro in order to determine if this inhibitor could act synergistically with a cancer vaccine.ResultsOur studies indicated that cabozantinib altered the phenotype of MC38-CEA murine tumor cells, rendering them more sensitive to immune-mediated killing.
Clinical significance of stanniocalcin expression in tissue and serum of gastric cancer patients.
New
Yi et al., Wuxi, China. In Chin J Cancer Res, 31 Oct 2014
The sensitivity of serum STC protein also showed superiority over CEA and CA19-9.
[Clinicopathological features associated with EGFR gene mutation in non-small cell lung cancer patients].
New
Zhou et al., Hangzhou, China. In Zhonghua Yi Xue Za Zhi, Sep 2014
The patients with mutant EGFR gene had a higher level of serum carcino-embryonic antigen (CEA) than those with wild-type EGFR gene (114.5 vs 41.8 µg/L, P = 0.038).
[Value of carcinoembryonic antigen levels in predicting the efficacy of EGFR-TKI in advanced non-small cell lung cancer harboring EGFR mutations].
New
Han et al., Shanghai, China. In Zhonghua Yi Xue Za Zhi, Sep 2014
OBJECTIVE: To explore the relevance of carcinoembryonic antigen (CEA) level and efficacy of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) in advanced non-small cell lung cancer (NSCLC) harboring EGFR mutations.
Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer.
Review
New
Peng et al., Jinan, China. In World J Gastroenterol, May 2014
METHODS: Serum cancer antigens (CA)199, CA242, carcinoembryonic antigen (CEA), and CA125 levels were measured in 78 patients with gallbladder cancer (GBC), 78 patients with benign gallbladder diseases, and 78 healthy controls using electrochemiluminescence.
[Doctor Francoise Cathala and history of prions diseases.]
Review
New
Hauw et al., Rouen, France. In Rev Neurol (paris), May 2014
A large number of research programs were set up with numerous collaborations involving CEA (Center for Atomic Energy) and other institutions in Paris and Marseilles on epidemiology, results of tissue inoculation, electrophysiology and neuropathology of human and animal prions diseases, and resistance of the infectious agent.
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data.
New
Impact
Michiels et al., Paris, France. In Lancet Oncol, Apr 2014
Carcinoembryonic antigen and cancer antigen 15-3 concentrations at baseline and during therapy did not add significant information to the best baseline model.
Benefits of using dexmedetomidine during carotid endarterectomy: A review.
Review
New
Nair, Hyderābād, India. In Saudi J Anaesth, Apr 2014
As per current recommendation, patients with acute ischemic stroke should be offered carotid endarterectomy (CEA) within 24-72 hours.
Prediction of response to preoperative chemoradiotherapy in patients with locally advanced rectal cancer.
Review
New
Yu et al., China. In Biosci Trends, Feb 2014
Magnetic resonance imaging (MRI), positron emission tomography-computed tomography (PET-CT), serum carcinoembryogenic antigen (CEA), molecular biomarkers analyzed by immunohistochemistry and gene expression profiling are the most used predictive models in LARC.
Signaling by epithelial members of the CEACAM family - mucosal docking sites for pathogenic bacteria.
Review
New
Hauck et al., Konstanz, Germany. In Cell Commun Signal, Dec 2013
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a group of immunoglobulin-related vertebrate glycoproteins.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Impact
Blumberg et al., Boston, United States. In Immunity, 2012
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on activated T cells and signals through either a long (L) cytoplasmic tail containing immune receptor tyrosine based inhibitory motifs, which provide inhibitory function, or a short (S) cytoplasmic tail with an unknown role.
HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens.
Review
GeneRIF
Hauck et al., Konstanz, Germany. In Arch Biochem Biophys, 2012
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
No correlation between pretreatment serum CEA levels and tumor volume in locally advanced rectal cancer patients.
GeneRIF
Kim et al., South Korea. In Clin Chim Acta, 2012
a positive correlation between CEA levels and survival
Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal cancer.
GeneRIF
Zhang et al., Harbin, China. In Onkologie, 2011
CEA mRNA, CK20 mRNA, and serum CEA than patients at stages I-III.
Efficacy of carcinogenic embryonic antigen in differential diagnosis of diseases of pancreas and liver--a comparative study in a tertiary care hospital of Western Nepal.
GeneRIF
Yadav et al., Pokhara, Nepal. In Asian Pac J Cancer Prev, 2011
High levels of carcinogenic embryonic antigen are associated with advanced stage of diseases of pancreas and liver.
Oxytocin selectively gates fear responses through distinct outputs from the central amygdala.
Impact
Stoop et al., Lausanne, Switzerland. In Science, 2011
Central amygdala (CeA) projections to hypothalamic and brain stem nuclei regulate the behavioral and physiological expression of fear, but it is unknown whether these different aspects of the fear response can be separately regulated by the CeA.
Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA.
GeneRIF
Feng et al., Xi'an, China. In World J Surg Oncol, 2010
High CEACAM7 is associated with gastric carcinoma.
Encoding of conditioned fear in central amygdala inhibitory circuits.
Impact
Lüthi et al., Basel, Switzerland. In Nature, 2010
The central amygdala (CEA), a nucleus predominantly composed of GABAergic inhibitory neurons, is essential for fear conditioning.
Carcinoembryonic antigen-related cell adhesion molecule-1 regulates granulopoiesis by inhibition of granulocyte colony-stimulating factor receptor.
Impact
Shively et al., Duarte, United States. In Immunity, 2010
Although carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is an activation marker for neutrophils and delays neutrophil apoptosis, the role of CEACAM1 in granulopoiesis and neutrophil-dependent host immune responses has not been investigated.
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