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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 11 Dec 2014.

Carcinoembryonic antigen-related cell adhesion molecule 5

CEA, Carcinoembryonic antigen
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, cytokeratin, V1a
Papers using CEA antibodies
Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
Supplier
Margel Shlomo et al., In Journal of Nanobiotechnology, 2010
... Haemek, Israel; LS174t and HT29 tumor cell lines from American Type Culture Collection (ATCC); monoclonal anti-CEA (T86-66) and anti-TAG-72 (CC-49) antibodies were purified from the hybridoma supernatant at Alomone Labs, Israel; human bowel juice ...
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
Supplier
Paul Marinus A. et al., In Pathology Research International, 1998
... E12, CK14 (Neomarkers), CK19, EMA, CEA (BioGenex), TTF-1, SP-A, CD56 (Novocastra), ...
Biliary Glycoprotein Messenger-Rna Expression Is Increased in Primary Lung-Cancer, Especially in Squamous-Cell Carcinoma.
Supplier
Navarro Alfons, In PLoS ONE, 1993
... Anti-human CEA/CEACAM5 mAb clone CI-P83-1 was obtained from Dianova (Hamburg, Germany) ...
Papers on CEA
Serum CA242, CA199, CA125, CEA, and TSGF are Biomarkers for the Efficacy and Prognosis of Cryoablation in Pancreatic Cancer Patients.
New
Feng et al., Luoyang, China. In Cell Biochem Biophys, 09 Jan 2015
UNLABELLED: This study aimed to compare the changes and determine the clinical significance of carbohydrate antigens CA242, CA199, CA125, carcinoembryonic antigen (CEA), and tumor-specific growth factor (TSGF) before and after cryoablation by Cryocare system.
Role of the IL-1 receptor antagonist in ethanol-induced regulation of GABAergic transmission in the central amygdala.
New
Roberto et al., Los Angeles, United States. In Brain Behav Immun, 02 Jan 2015
Studies of Il1rn knockout (KO) and wild type (WT) mice identified differences in several ethanol-related behaviors, some of which may be mediated by GABAergic transmission in the central nucleus of the amygdala (CeA).
Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain.
New
Stylianopoulou et al., Athens, Greece. In Psychoneuroendocrinology, 24 Dec 2014
Increased maternal behavior was experimentally induced by a brief 15-min separation between the mother and the pups during postnatal days 1 to 22. On postnatal days (PND) 12 and 22, we determined in experimental and control dams levels of anxiety in the elevated plus maze (EPM) as well as the levels of receptors for estrogens (ERα, ERβ), oxytocin (OTR) and serotonin (5-HT1AR) in areas of the limbic system (prefrontal cortex-PFC, hippocampus, lateral septum-SL, medial preoptic area-MPOA, shell of nucleus accumbens-nAc-Sh, central-CeA and basolateral-BLA amygdala), involved in the regulation of maternal behavior.
CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
New
Hammond et al., Gaithersburg, United States. In Mabs, 23 Nov 2014
Here the CEA and CD3 bispecific single-chain antibody MEDI-565 (also known as MT111 and AMG 211) was evaluated for its ability to activate T cells both in vitro and in vivo and to kill human tumor cell lines harboring various somatic mutations commonly found in colorectal cancers.
The Central Amygdala as an Integrative Hub for Anxiety and Alcohol Use Disorders.
Review
New
Roberto et al., New Orleans, United States. In Biol Psychiatry, Oct 2014
UNLABELLED: The central amygdala (CeA) plays a central role in physiologic and behavioral responses to fearful stimuli, stressful stimuli, and drug-related stimuli.
Nf1 Regulates Alcohol Dependence-Associated Excessive Drinking and Gamma-Aminobutyric Acid Release in the Central Amygdala in Mice and Is Associated with Alcohol Dependence in Humans.
New
Paolo Sanna et al., Boston, United States. In Biol Psychiatry, Sep 2014
METHODS: We assessed alcohol-related behaviors including alcohol sensitivity, dependent and nondependent drinking, and basal and alcohol-induced gamma-aminobutyric acid (GABA) release in the central nucleus of the amygdala (CeA) in Nf1 heterozygous null mice (Nf1(+/-)).
Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer.
Review
New
Peng et al., Jinan, China. In World J Gastroenterol, May 2014
METHODS: Serum cancer antigens (CA)199, CA242, carcinoembryonic antigen (CEA), and CA125 levels were measured in 78 patients with gallbladder cancer (GBC), 78 patients with benign gallbladder diseases, and 78 healthy controls using electrochemiluminescence.
[Doctor Francoise Cathala and history of prions diseases.]
Review
New
Hauw et al., Rouen, France. In Rev Neurol (paris), May 2014
A large number of research programs were set up with numerous collaborations involving CEA (Center for Atomic Energy) and other institutions in Paris and Marseilles on epidemiology, results of tissue inoculation, electrophysiology and neuropathology of human and animal prions diseases, and resistance of the infectious agent.
Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data.
New
Impact
Michiels et al., Paris, France. In Lancet Oncol, Apr 2014
Carcinoembryonic antigen and cancer antigen 15-3 concentrations at baseline and during therapy did not add significant information to the best baseline model.
Benefits of using dexmedetomidine during carotid endarterectomy: A review.
Review
New
Nair, Hyderābād, India. In Saudi J Anaesth, Apr 2014
As per current recommendation, patients with acute ischemic stroke should be offered carotid endarterectomy (CEA) within 24-72 hours.
Signaling by epithelial members of the CEACAM family - mucosal docking sites for pathogenic bacteria.
Review
New
Hauck et al., Konstanz, Germany. In Cell Commun Signal, Dec 2013
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a group of immunoglobulin-related vertebrate glycoproteins.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Impact
Blumberg et al., Boston, United States. In Immunity, 2012
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on activated T cells and signals through either a long (L) cytoplasmic tail containing immune receptor tyrosine based inhibitory motifs, which provide inhibitory function, or a short (S) cytoplasmic tail with an unknown role.
HemITAM signaling by CEACAM3, a human granulocyte receptor recognizing bacterial pathogens.
Review
GeneRIF
Hauck et al., Konstanz, Germany. In Arch Biochem Biophys, 2012
CEACAM3 promotes opsonin-independent phagocytosis of CEACAM-binding bacteria. CEACAM3 is the main driver for this process on human granulocytes.
No correlation between pretreatment serum CEA levels and tumor volume in locally advanced rectal cancer patients.
GeneRIF
Kim et al., South Korea. In Clin Chim Acta, 2012
a positive correlation between CEA levels and survival
Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal cancer.
GeneRIF
Zhang et al., Harbin, China. In Onkologie, 2011
CEA mRNA, CK20 mRNA, and serum CEA than patients at stages I-III.
Efficacy of carcinogenic embryonic antigen in differential diagnosis of diseases of pancreas and liver--a comparative study in a tertiary care hospital of Western Nepal.
GeneRIF
Yadav et al., Pokhara, Nepal. In Asian Pac J Cancer Prev, 2011
High levels of carcinogenic embryonic antigen are associated with advanced stage of diseases of pancreas and liver.
Oxytocin selectively gates fear responses through distinct outputs from the central amygdala.
Impact
Stoop et al., Lausanne, Switzerland. In Science, 2011
Central amygdala (CeA) projections to hypothalamic and brain stem nuclei regulate the behavioral and physiological expression of fear, but it is unknown whether these different aspects of the fear response can be separately regulated by the CeA.
Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA.
GeneRIF
Feng et al., Xi'an, China. In World J Surg Oncol, 2010
High CEACAM7 is associated with gastric carcinoma.
Encoding of conditioned fear in central amygdala inhibitory circuits.
Impact
Lüthi et al., Basel, Switzerland. In Nature, 2010
The central amygdala (CEA), a nucleus predominantly composed of GABAergic inhibitory neurons, is essential for fear conditioning.
Carcinoembryonic antigen-related cell adhesion molecule-1 regulates granulopoiesis by inhibition of granulocyte colony-stimulating factor receptor.
Impact
Shively et al., Duarte, United States. In Immunity, 2010
Although carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is an activation marker for neutrophils and delays neutrophil apoptosis, the role of CEACAM1 in granulopoiesis and neutrophil-dependent host immune responses has not been investigated.
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